Seungpyo graduated from Hanyang University, Korea with M.S. and B.S. degrees in polymer engineering. His research involved the synthesis of polyorganosilsesquioxanes for microelectronic applications at the Korea Institute of Science and Technology. In 2004, Seungpyo published a set of investigations indicating that nanoparticle can cause nanoscale holes in living cell membranes (Bioconjugate Chemistry 2004, 15, 774-782). Based on these efforts and excellence in course work, Seungpyo won the University of Michigan Overberger Award in 2004 for excellence in polymer research. He then began a series of experiments designed to test the polyvalent effect in the specific targeting of cancer cells. His poster on this work won the "Top Three Best Poster Award" at the fall 2005 MRS meeting. Seungpyo graduated with his PhD in Macromolecular Science and Engineering in 2006 and is now doing a post-doc in the Langer lab at MIT.
The Binding Avidity of a Nanoparticle-Base Multivalent Targeted Drug Delivery Platform. S. Hong, I. Majoros, B. G. Orr, J. R. Baker, Jr., M. M. Banaszak Holl. Chemistry and Biology 2007, 14, 107-115.
HPLC analysis of functionalized poly(amidoamine) dendrimers and the interaction between a folate-dendrimer conjugate and folate binding protein. X. Shi, X. Bi, T. R. Ganser, S. Hong, L. A. Myc, A. Desai, M. M. Banaszak Holl, J. R. Baker. The Analyst, 2006, 131, 842-848.
Interaction of Polycationic Polymers with Supported Lipid Bilayers and Cells: Nanoscale Hole Formation and Enhanced Membrane Permeability. S. Hong, P. R. Leroueil, E. K. Janus, J. L. Peters, M.-M. Kober, M .T. Islam, B. G. Orr, J. R. Baker, Jr., and M. M. Banaszak Holl. Bioconjugate Chemistry 2006, 17, 728-734. (An ACS Most-Cited Article 2006)
Physical Interactions of Nanoparticles with Biological Membranes:The Observation of Nanoscale Hole Formation. S. Hong, J. A. Hessler, M. M. Banaszak Holl, P. Leroueil, A. Mecke, B .G. Orr. Chemical Health and Safety 2006, 13, 16-20.
The Interaction of Polyamidoamine (PAMAM) Dendrimers with Supported Lipid Bilayers and Cells: Hole Formation and the Relation to Transport. S. Hong, A. U. Bielinska, A. Mecke, B. Keszler, J. L. Beals, X. Shi, L. Balogh, B. G. Orr, J. R. Baker Jr., and M. M. Banaszak Holl. Bioconjugate Chemistry 2004, 15, 774-782.