Gina R. Poe Ph.D.
| 7433 Medical Sciences I 0615 |
| Ann Arbor, MI 48109 |
Download this page 
Research in my lab combines interests in basic sleep processes, development, learning and memory, and optimization of cognitive performance. We use multiple microelectrodes to measure activity from tens of neurons simultaneously in the freely behaving animal hippocampus. We have found a neural discharge pattern that could explain why REM sleep is important to synaptic reorganization in general, which includes the synaptic changes that occur during learning and normal development.
Detailed investigation of these neural processes should uncover the normal mechanisms underlying the role of sleep in learning and memory and explain cognitive declines that parallel REM sleep disruptions, such as in certain cases of mental retardation and in the normal aging process.
Jablonski P, Poe G, Zochowski M. Structural network heterogeneities and network dynamics: a possible dynamical mechanism for hippocampal memory reactivation. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Jan;75(1 Pt 1):011912. Epub 2007 Jan 16 [Epub ahead of print]
Waddell J, Dzakpasu R, Booth V, Riley B, Reasor J, Poe G, Zochowski M. Causal entropies - A measure for determining changes in the temporal organization of neural systems. J Neurosci Methods, 2006 Dec 22 [Epub ahead of print]
Booth V, Poe GR. Input source and strength influences overall firing phase of model hippocampal CA1 pyramidal cells during theta: relevance to REM sleep reactivation and memory consolidation. Hippocampus, 16(2):161-73, 2006.
Bjorness TE, Riley BT, Tysor MK, Poe GR. REM restriction persistently alters strategy used to solve a spatial task. Learning and Memory, 12(3):352-9, 2005.
Poe GR, Rector DM, Harper RM. State-dependent columnar organization of dorsal hippocampal activity in the freely-behaving cat. Behavioral Brain Research, 138(1):107-12, 2003.
Poe GR, Thompson CM, Riley BT, Tysor MK, Bjorness TE, Steinhoff BP, Ferluga ED. A spatial memory task appropriate for electrophysiological recordings. Journal of Neuroscience Methods, 121(1):65-74, 2002.
Knierim JJ, McNaughton BL, Poe GR. Three-dimensional spatial selectivity of hippocampal neurons during space flight. Nature Neuroscience, 3:209-10, 2000.
Poe GR, Teed RG, Insel N, White R, McNaughton BL. Barnes CA. Partial hippocampal inactivation: effects on spatial memory performance in aged and young rats. Behavioral Neuroscience, 114:940-9, 2000.
Poe GR, Nitz DA, McNaughton BL, Barnes CA. Experience-dependent phase-reversal of hippocampal neuron firing during REM sleep. Brain Research, 855:176-80, 2000.
Find more publications by Dr.Gina Poe