Al-Hashimi, Hashim
Development and application of residual dipolar coupling-based NMR. Spectroscopy in studies of nucleic acids and their complexes.

Ballou, David
Mechanisms of biological redox reactions and reactions with oxygen; physical and chemical studies, especially rapid reaction techniques.

Banaszak Holl, Mark
Biophysics of nanoparticle and polymer interactions with cell membranes and applications ranging form environmental toxins to targeted drug delivery

Bardwell, James
Protein folding: role of molecular chaperones and disulfide catalysts.

Brooks, Charles
Theoretical and computational biophysics and chemistry; protein folding; multi-scale modeling of macromolecular motors (e.g., ribosomes, helicases); protein-ligand interactions and drug discovery/design (docking, free energy perturbation methods); viral capsid assembly, energetics and conformational transitions; large-scale conformational transitions in biological macromolecules; ion channel transport and selectivity mechanisms; membrane protein insertion, folding and assembly; GPCR and other integral membrane protein modeling and dynamics.

Carlson, Heather
Theory of protein-ligand binding.

Chen, Zhan
Biomaterial and polymer surfaces, biocompatibility, non-linear vibrational spectroscopy; lasers.

Crippen, Gordon
Novel methods in conformational analysis; distance geometry; computational studies of ligand binding, prediction of protein folding.

Fierke, Carol
Catalytic mechanism and structure-function analysis of metalloenzymes and ribozymes; protein engineering.

Gafni, Ari
Spectroscopic studies of protein structure; protein folding mechanisms and the role of chaperone proteins; single molecule studies of biomolecular interactions, amyloid generation and deposition in diabetes and Alzheimer’s disease.

Hunt, Alan
Physical and mechanical properties of molecular motors, particularly as pertains to the movements of chromosomes during mitosis. Design and use of systems for imaging and manipulating intracellular structures at the nanometer level.

Kerppola, Tom
Regulation of gene expression by proto-oncogene transcription factors; transcription factor interactions and nucleoprotein complex architecture.

Kopelman, Raoul
Biomedical nanosensors embedded in single cells and fiber-optic biochemical nanosensors; novel supermicroscopy techniques via Near-Field optics, laser fluorescence and energy transfer.

Krimm, Samuel (Emeritus)
Raman, and normal coordinate analyses of peptide and protein spectra and structure; development of molecular mechanics and dynamics energy functions.

Kubarych, Kevin
Physical and Biophysical Chemistry: Ultrafast nonlinear, multidimensional spectroscopy of biomolecules; optical control of biomolecular dynamics.

Lehnert, Nicolai
Biological chemistry of nitric oxide (NO), biophysical studies on NO reductases and related proteins using resonance Raman, EPR, and magnetic circular dichroism (MCD) spectroscopy.

Lei, Ming
Biochemical signaling, structural enzymology.

Lubensky, David
Systems biology. Computational and theoretical studies of biochemical and genetic networks. Biomechanics, especially applied to development and morphogenesis. Fluctuations in chemical
systems far from equilibrium.

Marsh, E. Neil G.
Enzymes; structure mechanism and specificity; protein engineering and molecular recognition.

Meiners, Jens-Christian
Single-molecule experiments with nucleic acids and nucleic acid protein complexes using laser tweezers; dynamics of single DNA molecules; mechanics of transcription and transcriptional regulation.

Meyhöfer, Edgar
Molecular motors, molecular-level description of mechanical processes such as muscular contraction, cell division and intracellular transport.

Ninfa, Alexander
Biochemical signaling, protein processing and folding, structural enzymology, regulations of gene expression.

Ogilvie, Jennifer
Ultrafast & non-linear optical methods for biological imaging and spectroscopy.

Palfey, Bruce
University of Michigan. Mechanisms of flavin-containing enzymes involved in pyrimidine metabolism.

Pecoraro, Vincent
Biological chemistry of manganese and vanadium; de novo design of metallopeptides.

Penner-Hahn, James
Structural characterization of metalloprotein metal sites; investigation of Zn biochemistry and the roles of Zn in development; development of new methods in x-ray absorption and fluorescence spectroscopy; characterization of the yeast metallome.

Raghavan, Malini
Biochemical and molecular interactions underlying immune recognition events: Interactions and biochemical mechanisms of function of the transporters associated with antigen processing; mammalian and viral Fc receptors and their interactions with immunoglobulin G.

Ramamoorthy, A.
Solid-state NMR spectroscopy; structural biology of membrane proteins; study of polymers.

Saper, Mark A.
Molecular mechanisms of bacterial pathogenesis, type III secretion, exopolysaccharide biosynthesis.  Crystal structure determination and biochemistry.

Savit, Robert
Theoretical physics, complex systems. Adaptive and evolutionary systems, nonlinear systems, nonlinear data analysis.

Sension, Roseanne
Ultrafast spectroscopic studies of enzyme mechanism.

Smith, Janet
Use of x-ray crystallography to determine the three-dimensional protein structure in order to understand the molecular mechanisms of biological processes. Current projects include studies of glutamine amidotransferases and replication machinery of alphaviruses and flaviviruses.

States, David
Current projects focus on the application of quantitative analytic methods, statistics and machine learning technology to problems of molecular biology and genome analysis.

Steel, Duncan
Development and application of advanced laser spectroscopy methods to studies of protein structures in solution; protein dynamics and protein folding.

Sunahara, Roger
Molecular mechanisms of G protein-coupled receptors signaling. Biochemistry and structural biology of G protein-coupled receptor signaling cascades.

Swanson, Joel
Quantitative fluorescence microscopy of signal transduction during endocytosis in macrophages.

Tesmer, John
Molecular basis of heterotrimeric G protein signal transduction.

Trievel, Ray
Post-translational modifications of proteins in the nucleus.  Crystallographic study of histone lysine methylation.

Verhey, Kristen
Molecular motors in protein and membrane trafficking. In vivo single molecule studies of kinesin motors. Molecular mechanisms of motor regulation by cargo and substrate.

Walter, Nils G.
Catalytic RNA, fluorescence resonance energy transfer, fluorescence lifetime, ribosome, ribozyme, RNA dynamics and structure, video fluorescence microscopy, atomic force microscopy.

Wang, Shaomeng
Structure-based design and synthesis of molecular target-specific novel small molecule drugs for treatment of cancer; Development and application of new methods for drug design and discovery; Computational studies of protein folding and protein-protein interactions.

Xu, Zhaohui
Protein-protein interaction and molecular recognition; structural biology of protein folding, protein translocation and cellular signal transduction; X-ray crystallography.

Young, Matthew

Zand, Robert
Spectroscopic and chemical assessment of structure, binding behavior, and properties of neuropeptide Y chimeras and receptors; posttranslational modification, evolution, and biological properties of myelin basic protein; synthesis of biopolymers and their nonlinear electrooptical properties.

Zochowski, Michal
Application of optical and electrophysiological techniques to monitor formation of spatio-temporal patterns in neural systems; investigating role and mechanisms of formation of oscillatory responses in the olfactory bulb.