Lecture Schedule

Class
Date Topic(s) Web Notes
1
Sept. 12, 2000

1) Short class discussion on expectations for the course

2) The relationship between research and applying the findings to your patients. (Dr. Lopatin)

3) Defining the clinical question: The first step in finding the answer. (Short lecture and group discussion)

 

Readings:

Lecture Notes

The Well-Built Clinical Question (A tutorial)

Richardson WS, Wilson MC, Nishikawa J, Hayward RSA. The well-built clinical question: a key to evidence-based decisions. ACP Journal Club. Nov-Dec 1995;123;A12.

Getting Evidence into practice (Series of articles from the British Medical Journal)

Asking focused questions (table)

Constructing a Focused Clinical Question (example)

2
Sept. 19, 2000

1) Class discussion of student clinical questions (from Homework assignment)

2) The publication process: From the clinical study to the database

Assignment (Develop a focused Clinical Question)

Readings for this session:

Lecture Notes

Responsible Conduct Regarding Scientific Communication Society for Neuroscience

3
Sept. 26, 2000

Class discussion on searching the scientific literature to answer a clinical question: How do you refocus and refine your clinical question when you can't find the answer (sensitivity and specificity)? The use of filters and "hedges" in focusing your search process

Assignment (Filters and hedges)

Readings:

Searching for the Best Evidence in Clinical Journals

Using Clinical Query Search Filters

Medline FAQs

During this class meeting we will create student discussion groups whose goal it will be to find several research reports that address issues in prevention, harm, diagnostic tests, prognosis, etc. (See assignment for next session)

4
Oct. 3, 2000

Searching the scientific databases for the answer to your clinical question: Using Web-based resources (Mrs. Anderson)

Assignment (Group project) to be turned in at the end of the week (October 6, by 5:00pm)

Readings:

Medline Glossary [When doing a Medline search, what does it mean to "explode" or "map" a term? How do "Limits" work? What is a "Boolean search"? Etcetera.]

Why Finding "Evidence" In Medline can be Frustrating (Librarian's Working Group)

Things to Keep in Mind When Searching Medline (Librarian's Working Group)

The Literature Search (Good Step-by-step example)

Worksheet for examining your question and building your strategy (Use page 1 of the file)

5
Oct. 10, 2000

1) Experimental Design Models (Dr. Kowalski)

2) Issues in Designing Randomized Control Trials (Dr. Kowalski)

Assignment (Study Design) to be turned in at the start of class

Readings:

Randomized Clinical Trials (From: British Dental Journal:Performing the electronic search) Read the first two chapters: 1) the Basics and Types of RCTs)

EBM Toolbox Read Comparison of Study Designs these designs are defined in the glossary)

Study Types (From Duke University Medical Center Library and University of North Carolina at Chapel Hill Health Science Library)

Papers: J. Dent Res 74:1453-1459, 1995 and Br. Dent. Journal 169:245-247, 1990.

6
Oct. 17, 2000

1) Ethical issues in research (Dr. Kowalski)

2) The role of the IRB (Dr. Kowalski)

Assignment (Peer review and ethics)

Readings:

Univ. of Michigan IRB Website (Examine content of site)

Ethical Principles and Human subjects research (Examine content of site)

Read Introduction to "on being a scientist" and scenarios. Each student will be assigned one scenario to discuss in class.

IRB Health website (Reviews Dental school applications) read application.

Download PowerPoint slides for this lecture

7
Oct. 24, 2000

Discussion of papers dealing with Therapy and Prevention (Discussion led by student discussion groups assigned topic of Therapy and Prevention)

Assignment (Therapy and Prevention)

Readings:

Evaluating the Evidence (Very good medical scenarios)

Evidence- Based Medicine Tool Box (download Therapy and Prevention Worksheets)

Articles to be discussed in class

8
Oct. 31, 2000

Discussion of papers dealing with Diagnostic Tests (Discussion led by student discussion groups assigned topic of Diagnostic Tests)

Assignment (Diagnostic Tests)

Readings:

Evidence- Based Medicine Tool Box (download Diagnostic Test Worksheets)

Articles to be discussed in class

9
Nov. 7, 2000

Discussion of papers dealing with Prognosis (Discussion led by student discussion groups assigned topic of Prognosis)

Assignment (Prognosis)

Readings:

Evidence- Based Medicine Tool Box (Download Prognosis Worksheets)

Articles to be discussed in class

10
Nov. 14, 2000

Discussion of papers dealing with Harm (Discussion led by student discussion groups assigned topic of Harm)

Assignment (Harm)

Readings:

Evidence- Based Medicine Tool Box (download Harm Worksheets)

Articles to be discussed in class

11
Nov. 21, 2000

Meta analysis (Dr. Kowalski)

Assignment (Meta-analysis)

Readings:

Introduction to Systematic Reviews Read: Introduction (What is systematic review)and Meta-analysis (What is Meta-analysis?)

Evidence-Based Medicine Toolkit (download worksheet on systematic reviews)

Article: J. Dent Res. 72:1509-1518, 1993.

12
Nov. 28, 2000

Evidence-based Dentistry: The Movement (Dr. Ismail)

Assignment (Systematic Reviews)

Readings:

 

13
Dec. 5, 2000

Putting it together: Reports from the Field (Invited Guests in Roundtable format)

Assignment (final project)

 

 

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