Pragani, R.; Seeberger, P. H. J. Am. Chem. Soc. 2011, 133, 102-107.

 

 

The students of Han's 215HH SSG are at a relaxing vacation in Disney World, enjoying some great scenery and movie themed attractions. Suddenly, after getting off that awesome spinning teacup ride, they see an evil army of minions invading the park and wreaking general havoc! When interrogated by a daring student of the class, one of the minions breaks down and admits that the army is led by a diabolical chemist, who has inoculated the army with bacteria in hopes of infecting the unsuspecting Disney characters. Luckily, the students in SSG remember that Pragani et al. have recently discovered how to synthesize Zwitterionic Polysaccharide A1 repeating unit, an immunomodulatory agent that can activate the T-cell dependent immune response through MHC II presentation. Follow the brave students in their quest to read the literature, synthesize the polysaccharide, and prevent utter chaos from being unleashed!