FINDING YOUR MOLECULE

The first handout is included below.
Your Personal Molecule. First Handout.



1. AZT (3’-Azido-3’-deoxythymidine) Journal of Organic Chemistry, 61, 895-902.

for 14a-c, R1 = N3 and R2 = H

2. Vitamin A (All-trans-retinol) Journal of Biological Chemistry, 269, 29613-29602.

3. Colchicine Journal of Organic Chemistry, 59, 4285-4296.

4. Riboflavin (Vitamin B2) Journal of Organic Chemistry, 60, 2646-2647.

Top Scheme I

5. Estradiol Journal of Organic Chemistry, 60,5316-5318.

for 1, R = H

6. penicillin G Journal of Organic Chemistry, 59, 5858-5861.


7. vanillin Journal of Chemical Education, 70, A155-6+

(“A” pages are at the beginning of each journal)

8. warfarin Journal of the American Chemical Society, 83, 2676-2679.

(-)(S) - I

9. procaine (HCl salt = novocain) Journal of Medicinal Chemistry, 17, 151-154.

the structure under “...according to Coubeil’s and Pullman’s calculations the following compound...”
n = 2


10. dioxin Journal of Organic Chemistry, 41, 2435-2437.

(1), 2,3,8,7 -Cl

11. isoniazid Journal of he American Chemical Society, 117, 5009-5010.

12. caffeine Journal of Organic Chemistry, 55, 4988-4989.

Upper left of scheme II
X = H

13. 6-mercaptopurine (6-MP) Inorganic Chemistry, 31, 4628-4634.

14. dopamine Journal of Organic Chemistry, 62, 6582-6587.

15. serotonin (5-HT) Journal of Organic Chemistry, 62, 8640-8653.