BME 499.098/Biostat 642:
Introduction to Functional MRI



Schedule & Basic Info

Class Meeting Time: 9AM to Noon, Monday-Friday, Aug 12 through Aug 23
Class Meeting place: East Hall 1068 & 1360; see calendar
 
Lab Meeting Time: 1PM-3PM
Lab Meeting place: East Hall B250, PC lab in the basement of East Hall (except as noted)
 
Instructors: Luis Hernandez, Tom Nichols, & Doug Noll
Announcements: If you didn't already, please fill out a Course Evaluation and return it to Eve Gochis in the fMRI lab.

Course Calendar

 Week 1
  Mon 8/12 Tue 8/13 Wed 8/14 Thu 8/15 Fri 8/16
 
Lecture
9am-
Noon
Physics I: NMR, Fields, Gradients (DN)
Rm: EH 1068
Physics II: Image formation, SNR, Hardware (DN)
Rm: EH 1068
Physics III: BOLD Effect. Artfacts (DN)
Rm: EH 1360
Task Design I: Subtraction, Blocked & event-related designs (DN)
Rm: EH 1068
Artifacts, image reconstruction, preprocessing (LH)
Rm: EH 1360
 
Lab
1pm-
3pm
Task Design: E' (TW) Task Design: E' (TW) fMRI Lab: Safety, tour, scanning. Group A
Rm: fMRI Lab
fMRI Lab: Safety, tour, scanning. Group B
Rm: fMRI Lab
Matlab intro, Data exploration
 
 Week 2
  Mon 8/19 Tue 8/20 Wed 8/21 Thu 8/22 Fri 8/23
Lecture
9am-
Noon
Stats I: General Linear Model (TN)
Rm: EH 1360
Stats II: fMRI Modeling (TN)
Rm: EH 1360
Stats III: Multiple comparisons, Group analyses (TN)
Rm: EH 1360
Task Design II: Optimizing ER, jitter, nonlinearity (TW)
Rm: EH 1360
Presentations, Q & A
Rm: EH 1360
 
Lab
1pm-
3pm
SPM I: Intro, preprocessing (TN/LH) SPM II: Intrasubject results (TN/LH) SPM III: Group analyses, project work Monitored lab time (none)
 

Week 1

Mon Aug 12 Lecture: Physics
Instructor: Doug Noll
See Doug's
webpage

Mon Aug 12 Lab: Task Design I
Instructor: Tor Wager
Resources:

  • Sample E-prime experiments: FMRIBase_1dot1beta.zip, R9_UM_fmriBase.zip, IFISR9_visual_paradigms.zip.
  • Presentation slides Tor_E-Prime_20Aug_202002.ppt

  • Tue Aug 13 Lecture: Physics
    Instructor: Doug Noll
    See Doug's
    webpage

    Tue Aug 13 Lab: Task Design II
    Instructor: Tor Wager
    See resources for
    previous lab


    Wed Aug 14 Lecture: Physics
    Instructor: Doug Noll
    See Doug's
    webpage

    Wed Aug 14 Lab: fMRI Lab Tour (Group A)
    Instructor: Luis Hernandez & Doug Noll


    Thu Aug 15 Lecture: Task Design I
    Instructor: Doug Noll
    See Doug's
    webpage

    Thu Aug 15 Lab: fMRI Lab Tour (Group B)
    Instructor: Luis Hernandez & Doug Noll


    Fri Aug 16 Lecture: Artifacts II
    Instructor: Luis Hernandez

    Fri Aug 16 Lab: Matlab
    Instructor: Tor Wager


    Week 2

    Mon Aug 19 Lecture: Stats I
    Instructor: Tom Nichols
    Slides
  • Basic Stats
  • Matlab example & figures
  • Mon Aug 19 Lab: SPM I
    Instructor: Tom Nichols & Luis Hernandez
    Lab

  • Intro to SPM & Block Design Anlaysis


  • Tue Aug 20 Lecture: Stats II
    Instructor: Tom Nichols

  • Temporal Modeling
  • Tue Aug 20 Lab: SPM II
    Instructor: Tom Nichols & Luis Hernandez
    Lab

  • Intra- & Intersubject registration, & Event Related Anlaysis.


  • Wed Aug 21 Lecture: Stats III
    Instructor: Tom Nichols

  • Combining Statistic Images
  • Spatial Inference/Modeling
  • Introduction to SPM
  • Nonparametric FWE and FDR thresholding methods
  • Assignments: Homework & Project

    Wed Aug 21 Lab: SPM III
    Instructor: Tom Nichols & Luis Hernandez
    Lab

  • Evaluating intersubject registration & statistical model fit


  • Thu Aug 21 Lecture: Task Design II
    Instructor: Tor Wager

    Thu Aug 21 Lab: Monitored Lab Time
    Instructor: Tom Nichols & Luis Hernandez
    You will use this time to work on your project

    These files are useful additions to SPM:

    To put use these files follow these steps:
  • Find your spm99 directory. At the same level as (not in!!!) the spm99 directory create a "spm99_local" directory. This will contain your local modifications to SPM.
  • Download the two files above. Put them in spm99_local
  • Using "Set path..." or editpath add the spm99_local directory to your Matlab path above the spm99 directory


  • Fri Aug 21 Lecture: Class Presentations!
    Instructor: You!

    Fri Aug 21 Lab: none


    Final Project

    Final project assignment, culminating in presentations on the last day.


    Last modified: Sun Jul 11 11:10:06 EDT 2004

    Tom Nichols   nichols@umich.edu
    UM Biostatistics