Publications – DNA bending

· Ramirez-Carrozzi, V. R. and Kerppola, T. K. Control of the orientation of Fos-Jun binding and the transcriptional cooperativity of Fos-Jun–NFAT1 complexes. J. Biol. Chem. 276:21797-21808, 2001. [Abstract] [Full text] [PDF]

· Ramirez-Carrozzi, VR and Kerppola, TK: Dynamics of Fos-Jun-NFAT1 complexes. Proc. Natl. Acad. Sci. U.S.A. 98:4893-4898, 2001. [Abstract] [Full text] [PDF]

· Dlakic M, Grinberg, AV, Leonard, DA and Kerppola, TK: DNA sequence-dependent folding determines the divergence in binding specificities between Maf and other bZIP proteins. EMBO Journal 20: 828‑840, 2001. [Abstract] [Full text] [PDF]

· Ramirez-Carrozzi, VR and Kerppola, TK: Long-range electrostatic interactions influence the orientation of Fos-Jun binding at AP-1 sites. J. Mol. Biol. 305: 411-427, 2001. [Abstract] [Full text] [PDF]

· Kerppola, TK: Molecular architecture of transcription-regulatory protein complexes. HHMI Research in Progress, p. 327-328, 2000. [Full text]

· Dlakic, M and Kerppola, TK: DNA structure changes coupled to protein binding. Encyclopedia of Life Sciences, Macmillan Reference Ltd., 2000. [Home page]

· Leonard, DA and Kerppola, TK: DNA bending determines Fos-Jun heterodimer orientation. Nature Structural Biology, 5:877-881, 1998. [Abstract] [Full text] [PDF]

· Kerppola, TK: Transcriptional cooperativity: bending over backwards and doing the flip. Structure, 6:549-554, 1998. [Abstract] [Full text] [PDF]

· Diebold, RJ, Rajaram, N, Leonard, D.A and Kerppola, TK: Molecular basis of cooperative DNA bending and oriented heterodimer binding in the NFAT1-Fos-Jun-ARRE2 complex. Proc. Natl. Acad. Sci. U.S.A., 95:7915-7920, 1998. [Abstract] [Full text] [PDF]

· Kerppola, TK: Molecular architecture of transcription factor complexes. HHMI Research in Progress, p. 339-340, 1997-1998. [Full text]

· Rajaram, N and Kerppola, TK: DNA bending by Fos-Jun and the orientation of heterodimer binding depend on sequence of the AP-1 site. EMBO J, 16:2917-2926, 1997. [Abstract] [Full Text] [PDF]

· Kerppola, TK and Curran, T: The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J, 16:2907-2916, 1997. [Abstract] [Full Text] [PDF]

· Leonard, D, Rajaram, N and Kerppola, TK: Structural basis of DNA bending and oriented heterodimer binding by Fos and Jun. Proc. Natl. Acad. Sci. U.S.A., 94:4913-4918, 1997. [Abstract] [Full Text] [PDF]

· Kerppola, TK: Comparison of DNA bending by Fos-Jun and phased A tracts by multifactorial phasing analysis. Biochemistry, 36:10872-10884, 1997. [Abstract] [Full Text] [PDF]

· Kerppola, TK: Molecular architecture of transcription factor complexes. HHMI Biennial Scientific Report, p. 76-77, 1996-1998.

· Kerppola, TK: Mechanisms of transcriptional cooperativity. HHMI Research in Progress, p. 315-316, 1996. [Full text]

· Kerppola, TK: Fos and Jun bend the AP-1 site: Effects of probe geometry on the detection of protein induced DNA bending. Proc. Natl. Acad. Sci. U.S.A., 93: 10117-10122, 1996. [Abstract] [PDF]

· Kerppola, TK: Mechanisms of transcriptional cooperativity. HHMI Annual Scientific Report, 86-87, 1995-96.

· Kerppola, TK and Curran, T: Zen and the art of Fos and Jun. Nature, 373: 199-200, 1995.

· Kerppola, TK and Rajaram, N: Sequence dependence of DNA bending by Fos and Jun. Biopolymers Gordon Research Conference (C. Bustamante), Newport, Rhode Island, 1996.

· Kerppola, TK: Fos and Jun bend the AP-1 site: Effects of probe geometry on the detection of protein induced DNA bending. Proc. Natl. Acad. Sci. U.S.A., 93: 10117-10122, 1996. [Abstract] [PDF]

· Kerppola, TK: Mechanisms of transcriptional cooperativity. HHMI Annual Scientific Report, 86-87, 1995-96.

· Kerppola, TK and Curran, T: Zen and the art of Fos and Jun. Nature, 373: 199-200, 1995.

· Kerppola, TK: DNA bending specificity among bZIP family proteins. In Transcription: Mechanisms & Regulation (ed. R. Conaway and J. Conaway), Raven Press, New York, pp. 387-424, 1994.

· Kerppola, TK: DNA bending specificity among bZIP family proteins. In Transcription: Mechanisms & Regulation (ed. R. Conaway and J. Conaway), Raven Press, New York, pp. 387-424, 1994.

· Kerppola, TK and Curran, T: Fos, Jun and GR: Structural and functional interactions. 75th Annual Meeting of the Endocrine Society, Las Vegas, Nevada, p. 20, 1993.

· Kerppola, TK, Wang, Y, Griffith, J and Curran, T: Role of DNA bending in transcription activation by Fos and Jun family proteins. LVIII Cold Spring Harbor Symposium on Quantitative Biology, DNA and Chromosomes (B. Alberts, B. Stillman), Cold Spring Harbor, New York, p. 90, 1993.

· Kerppola, TK and Curran, T: Selective DNA bending by a variety of bZIP proteins. Molecular and Cell Biology, 13 (9): 5479-5489, 1993. [Abstract]

· Kerppola, TK, Robertson, LM and Curran, T: DNA bending, protein-protein interactions, and the regulation of c-fos expression. Molecular Basis of Cell Proliferation Gordon Research Conference (T. Curran and R. Eisenberg), Meriden, New Hampshire, 1993.

· Kerppola, TK and Curran, T: Selective DNA bending by a variety of bZIP proteins. Molecular and Cell Biology, 13 (9): 5479-5489, 1993. [Abstract]

· Kerppola, TK and Curran, T: Role of DNA bending in transcription activation and regulatory specificity among Fos and Jun family proteins. Journal of Cellular Biochemistry, 17A (6): 79, 1993.

· Kerppola, TK and Curran, T: DNA bending by Fos and Jun: Structural and functional implications. In Nucleic Acids and Molecular Biology Vol. 7 (ed. F. Eckstein and D. Lilley), Springer-Verlag, London, pp. 70-105, 1993.

· Kerppola, TK and Curran, T: DNA bending by Fos and Jun: The flexible hinge model. Science, 254: 1210-1214, 1991.

· Kerppola, TK and Curran, T: Fos–Jun heterodimers and Jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity. Cell, 66: 317-326, 1991. [Abstract]

· Kerppola, TK and Kane, CM: Analysis of the signals for transcription termination by purified RNA polymerase II. Biochemistry 29: 269-278, 1990. [Abstract]

· Kerppola, TK and Kane, CM: Intrinsic sites of transcription termination and pausing in the c-myc gene. Molecular and Cell Biology, 8 (10): 4389-4394, 1988.