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1420 Lurie Biomedical Engineering Building
1101 Beal Ave., Ann Arbor, MI
Tel: (734) 764-3676 Fax:(734) 936-1905
THE HUNT LAB
Rapid Microtubule Self-Assembly Kinetics published in Cell
BME Professor Alan J. Hunt has published a groundbreaking paper in the August 21, 2011 issue of Cell. The paper titled “Rapid Microtubule Self-Assemblly Kinetics” describes a multi-investigator effort growing from a collaboration between Professor Hunt’s own lab and Professor David Odde and his group at the Univeristy of Minnesota. This work fundamentally changes our understanding of how a critical cellular component, microtubules, are formed and regulated. In addition to fundamentally impacting our understanding of cell biology, it also has important implications for chemotherapy, as microtubule polymerization dynamics are one of the most important targets for anticancer drugs. The experimental work involves advanced technologies for nanometer-scale studies of microtubule polymerization, and computer modeling. The abstract and full article can be viewed online.
Primary Investigator:
Alan J. Hunt, Ph.D.
Post-Graduate Students:
Blake Charlebois, Ph.D.
Cuie Chen, Ph.D.
Damon Hoff, Ph.D.
Aghapi Mordovanakis, Ph.D.
Graduate Students:
Seth McCubbin
Hong Zhou
Undergraduate Students:
Vishhvaan Gopalakrishnan
Collaborators:
Joe Bull, Ph.D.,
University of Michigan
Biomedical Engineering
Duane Compton, Ph.D.
Dartmouth University
Biochemistry Department
Holly Goodson, Ph.D.
University of Notre Dame
Chemistry and Biochemistry
Jay Guo, Ph.D.
University of Michigan
Electrical Engineering and Computer Science
Ernest C. Hasselbrink Jr., Ph.D.
University of Michigan
Mechanical Engineering
Charles Lindemann, Ph.D.
Oakland University
Biological Sciences
Michael Mayer, Ph.D.
University of Michigan
Biomedical Engineering
Edgar Meyhofer, Ph.D.
University of Michigan
Mechanical Engineering
David Odde, Ph.D.
University of Minnesota
Biomedical Engineering
Yukiko Yamahita, Ph.D.
University of Michigan
Life Sciences Institute
Alumni:
Ran An, Ph.D.
McMaster University
Post-doctoral Research Fellow
Matt Beneke
TomoTherapy Inc. in Madison, WI
Gary Brouhard, Ph.D.
McGill University
Assistant Professor
Jun Cheng, Ph.D.
University of Illinois
Bioengineering
Mindy Chilman
Leonard Chu
University of Michigan
Orthopaedics Research Laboratory
Elissa Cosgrove
Boston University
Gardner Laboratory
Jeff Herbstman, Ph.D.
University of Michigan
Skiniotis Laboratory
Diana Hilton
University of Michigan
Fierke Group
Ajit Joglekar, Ph.D.
University of North Carolina, Chapel Hill
Salmon Laboratory
Kevin Ke, Ph.D.
University of Michigan
Mohammed Islam Group
Shaun Kennedy
University of Michigan
Biophysics Program
Sanghyun Lee, Ph.D.
Pohang University of Science and Technology (POSTECH)
David Lorch, Ph.D.
Brown University
Life and Physical Sciences
Laura McIntyre
University of Michigan
Medical School
Pratik Rohatgi
University of Michigan
Medical School
Aaron Rury
University of Michigan
Sension Group
Henry T. Schek, III, Ph.D.
89 North
Eric Tkaczyk
University of Michigan
Medical School
You have reached the website of the Cellular and Molecular Biomechanics Laboratory (CMBL) at The University of Michigan. Our laboratory investigates the physical and mechanical properties of the molecular motors that underlie biologic motility. We design and use systems for imaging and manipulating subcellular structures at the micro-and nano-meter level. Click on the links above to find out more about the CMBL or click here to visit the Biomedical Group at the Center for Ultrafast Optical Science (CUOS)
Lab Members in Picture: [Top] Blake Charlebois, Seth McCubbin, Damon Hoff, Aghapi Mordovanakis, Aslan Dizaji, [Bottom] Hong Zhou, Alan Hunt, Cuie Chen
