Joel A. Swanson
Publications: View pdf

1.   Swanson, J. A. &  G. L. Floyd.  1978. Fine structure of the zoospores and thallus of Blidingia minimaTrans. Amer. Micros. Soc. 97: 549-558.
2.   Swanson, J. A. & G. L. Floyd.  1979. Acid phosphatase in Asteromonas gracilis (Chlorophyceae, Volvocales): a biochemical and cytochemical characterization.  Phycologia 18: 362-368.
3.   Floyd, G. L.; H. J. Hoops & J. A. Swanson.  1980. Fine structure of the zoospore of Ulothrix belkae with emphasis on the flagellar apparatus.  Protoplasma 104: 17-31.
4.   Luna, E. J.; V. M. Fowler; J. Swanson; D. Branton & D. L. Taylor.  1981. A membrane cytoskeleton from Dictyostelium discoideum. I. Identification and partial characterization of an actin-binding activity.  J. Cell Biol. 88: 396-409.
5.   Swanson, J. A.; D. L. Taylor & J. T. Bonner.  1981. Coated vesicles in Dictyostelium discoideumJ. Ultrastr. Res. 75: 243-249.
6.   Salisbury, J. L.; J. A. Swanson; G. L. Floyd; R. Hall & N. J. Maihle.  1981.  Ultrastructure of the flagellar apparatus of the green alga Tetraselmis subcordiformis. With special consideration given to the function of the rhizoplast and rhizanchora.  Protoplasma  104: 1-11.
7.   Hoops, H. J.; G. L. Floyd & J. A. Swanson.  1982. Ultrastructure of the biflagellate motile cells of Ulvaria oxysperma (Kutz.) Bliding and phylogenetic relationships among ulvaphycean algae.  Amer. J. Bot. 69: 150-159.
8.   Taylor, D. L.; J. Heiple; Y. -L. Wang; E. J. Luna; L. Tanasugarn; J. Brier; J. Swanson; M. Fechheimer; P. Amato; M. Rockwell & G. Daley.  1982. Cellular and molecular aspects of amoeboid movement.  Cold Spring Harbor Symp. Quant. Biol. v. XLVI 101-111.
9.   Swanson, J. A. & D. L. Taylor.  1982. Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis.  Cell 28: 225-232.
10. Brier, J.; M. Fechheimer; J. Swanson & D. L. Taylor.  1983. Abundance, relative gelation activity, and distribution of the 95,000-dalton actin-binding protein from Dictyostelium discoideumJ. Cell Biol. 97: 178-185.
11. Swanson, J. A.; B. D. Yirinec & S. C. Silverstein.  1985. Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages.  J. Cell Biol. 100: 851-859.
12. Bonner, J. T.; B. D. Joyner; A. A. Moore; H. B. Suthers & J. A. Swanson.  1985. Successive asexual life cycles of starved amoebae in the cellular slime mould Dictyostelium mucoroides var. stoloniferumJ. Cell Sci. 77: 19-26.
13. McNeil, P. L.; J. A. Swanson; S. D. Wright; S. C. Silverstein & D. L. Taylor.  1986. Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i.  J. Cell Biol. 102: 1586-1592.
14. Swanson, J.; B. Yirinec; E. Burke; A. Bushnell & S. C. Silverstein.  1986. Effect of alterations in the size of the vacuolar compartment on pinocytosis in J774.2 macrophages.  J. Cell. Physiol. 128: 195-201.
15. Swanson, J.; A. Bushnell & S. C. Silverstein.  1987. Tubular lysosome morphology and distribution within macrophages depend on the integrity of cytoplasmic microtubules.  Proc. Nat. Acad. Sci. U.S.A. 84: 1921-1925.
16. Swanson, J.; E. Burke & S. C. Silverstein.  1987. Tubular lysosomes accompany stimulated pinocytosis in macrophages.  J. Cell Biol. 104: 1217-1222.
17. Steinberg, T. H.; A. S. Newman; J. A. Swanson & S. C. Silverstein.  1987. ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes.  J. Biol. Chem. 262: 8884-8888.
18. Steinberg, T. H.; A. S. Newman; J. A. Swanson & S. C. Silverstein.  1987.  Macrophages possess probenecid-inhibitable organic anion transporters that remove fluorescent dyes from the cytoplasmic matrix.  J. Cell Biol. 105: 2695-2702.
19. Swanson, J. A. & P. L. McNeil.  1987. Nuclear reassembly excludes large macromolecules.  Science 238: 548-550.
20. DiVirgilio, F.; T. H. Steinberg; J. A. Swanson & S. C. Silverstein.  1988.  Fura-2 secretion and sequestration in macrophages.  A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions.  J. Immunol. 140: 915-920.
21. Swanson, J. & S. C. Silverstein.  1988. Pinocytic flow through macrophages.  In: Processing and Presentation of Antigens.  Pernis, B., S. C. Silverstein & H. Vogel, eds.  Academic Press, NY. pp. 15-27.
22. Steinberg, T. H.; J. A. Swanson & S. C. Silverstein.  1988. A prelysosomal compartment sequesters membrane-impermeant fluorescent dyes from the cytoplasmic matrix of J774 macrophages.  J. Cell Biol. 107: 887-896.
23. Swanson, J.  1989.  Fluorescent labeling of endocytic compartments.  In: Fluorescence Microscopy of Living Cells in Culture (Vol. 29 of Methods in Cell Biology) Y.L. Wang & D.L. Taylor, eds. Academic Press, NY. pp.137-151.
24. Swanson, J.  1989.  Phorbol esters stimulate macropinocytosis and solute flow through macrophages.  J. Cell Sci. 94: 135-142.
25. Racoosin, E. L. and J. A. Swanson.  1989.  Macrophage colony stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages.  J. Exp. Med. 170: 1635-1648.
26. Knapp, P. E. & J. A. Swanson.  1990.  Plasticity of the tubular lysosomal compartment in macrophages.  J. Cell Sci. 95: 433-439.
27. Hollenbeck, P. J. & J. A. Swanson.  1990.  Radial extension of macrophage tubular lysosomes supported by kinesin.  Nature 346: 864-866.
28. Swanson, J. A.; M. Lee & P. E. Knapp.  1991.  Cellular dimensions affecting the nucleocytoplasmic volume ratio.  J. Cell Biol. 115: 941-948.
29. Cannon, G. J. & J. A. Swanson.  1992.  The macrophage capacity for phagocytosis.  J. Cell Sci.  101: 907-913.
30. Racoosin, E. L. & J. A. Swanson.  1992.  M-CSF-induced macropinocytosis increases solute endocytosis but not receptor-mediated endocytosis in mouse macrophages.  J. Cell Sci.  102: 867-880.
31. Swanson, J. A.; A. Locke; P. Ansel & P. J. Hollenbeck.  1992.  Radial movement of lysosomes along microtubules in permeabilized macrophages.  J. Cell Sci.  103: 201-209.
32. Alpuche-Aranda, C. M.; J. A. Swanson; W. P. Loomis & S. I. Miller.  1992.  Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes.  Proc. Nat. Acad. Sci. U.S.A.  89: 10079-10083.
33. Racoosin, E. L. & J. A. Swanson.  1993.  Macropinosome maturation and fusion with tubular lysosomes in macrophages.  J. Cell Biol. 121: 1011-1020.
34. Swanson, J. A.  1993.  Pure thoughts with impure proteins.  Permeabilized cell models of organelle motility.  BioEssays 15:  715-722.
35. Steinberg, T. H. & J. A. Swanson.  1994.  Measurement of phagosome-lysosome fusion and phagosomal pH.  Methods in Enzymol.  236: 147-160.
36. Alpuche-Aranda, C. M.; E. L. Racoosin; J. A. Swanson & S. I. Miller.  1994.  Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes.  J. Exp. Med.  179: 601-608.
37. Racoosin, E. L. & J. A. Swanson.  1994.  Labeling of endocytic vesicles using fluorescent probes for fluid-phase endocytosis.  In: Cell Biology: A Laboratory Handbook.  J.E. Celis, ed.  Academic Press, NY. pp. 375-380.
38. Swanson, J. A. & S. C. Baer.  1995.  Phagocytosis by zippers and triggers.  Trends in Cell Biol.  5: 89-93.
39. Berthiaume, E. P.; C. Medina & J. A. Swanson.  1995.  Molecular size-fractionation during endocytosis in macrophages.  J. Cell Biol.  129: 989-998.
40. Rosania, G. & J. A. Swanson.  1995.  Effects of macromolecular crowding on nuclear size.  Exp. Cell Res.  218: 114-122.
41. Steinman, R. M. and J.  Swanson.  1995.  The endocytic activity of dendritic cells.  J. Exp. Med. 182:  283-288.
42. Swanson, J. A. & C. Watts.  1995.  Macropinocytosis.  Trends in Cell Biol.  5: 424-428.
43. Alpuche-Aranda, C. M.; E. P. Berthiaume; B. Mock; J. A. Swanson & S. I. Miller.  1995.  Spacious phagosome formation within mouse macrophages correlates with Salmonellae serotype pathogenicity and host susceptibility.  Infection and Immunity  63: 4456-4462.
44. Oh, Y. -K. & J. A. Swanson.  1996.  Different fates of phagocytosed particles after delivery into macrophage lysosomes.  J. Cell Biol.  132: 585-593.
45. Lee, K. -D.; Y. -K. Oh; D. A. Portnoy & J. A. Swanson.  1996.  Delivery of macromolecules into cytosol using liposomes containing hemolysin from Listeria monocytogenesJ. Biol. Chem. 271: 7249-7252.
46. Rosania, G. R. & J. A. Swanson.  1996.  Microtubules can modulate pseudopod activity from a distance inside macrophages.  Cell Motility Cytoskel.  34: 230-245.
47. Oh, Y. -K.; C. M. Alpuche-Aranda; E. P. Berthiaume; T. Jinks; S. I. Miller & J. A. Swanson.  1996.  Rapid and complete fusion of macrophage lysosomes with phagosomes containing Salmonella typhimuriumInfection and Immunity 64: 3877-3883.
48. Araki, N., M. T. Johnson & J. A. Swanson.  1996.  A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis in macrophages.  J. Cell Biol.  135: 1249-1260.
49. Oh, Y. -K.; C. V. Harding & J. A. Swanson.  1997.  The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation.  Vaccine  15: 511-518.
50. Beauregard, K. E., K.-D. Lee, R. J. Collier & J. A. Swanson.  1997.  pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenesJ. Exp. Med. 186: 1159-1163.
51. Araki, N. & J. A. Swanson.  1998. Labeling of endocytic vesicles using fluorescent probes for fluid-phase endocytosis.  In: Cell Biology: A Laboratory Handbook. Vol. 2.  (2nd edition) J.E. Celis, ed.  Academic Press, NY. pp. 495-500.
52. Swanson, J. A., M. T. Johnson, K. Beningo, P. Post, M. Mooseker & N. Araki.  1999.  A contractile activity that closes phagosomes in macrophages.  J. Cell Sci. 112: 307-316.
53. Barker, S.L.R., H. A. Clark, S. F. Swallen, R. Kopelman, A. W. Tsang and J. A. Swanson.  1999. Development and applications of ratiometric and fluorescence lifetime based biosensors for detection of extra- and intracellular macrophage nitric oxide.  Anal. Chem. 71: 1767-1772.
54. Swanson, J. A.  1999. Pathways through the macrophage vacuolar compartment.  In: Advances in Cell and Molecular Biology of Membranes and Organelles, Vol. 5, Phagocytosis: The Host.   S. Gordon, ed., JAI Press, NY. pp. 265-282.
55. Sund, S. E., J. A. Swanson and D. Axelrod.  1999.  Cell membrane curvature visualized by polarized total internal reflection fluorescence.  Biophys. J. 77: 2266-2283.
56. Beauregard, K. E., R. J. Collier and J. A. Swanson.  2000.  Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization.  Cell. Microbiol. 2: 251-258.
57. Tsang, A. W., K. Oestergaard, J. T. Myers and J. A. Swanson.  2000.  Altered membrane trafficking in activated bone marrow-derived macrophages.  J. Leukoc. Biol. 68: 487-494.
58.  Dixon, T. C., A. A. Fadl, T. M. Koehler, J. A. Swanson and P. C. Hanna.  2000.  Early Bacillus anthracis-macrophage interactions: intracellular survival and escape.  Cell. Microbiol. 2: 453-463.
59.  Christensen, K. A., J. T. Myers and J. A. Swanson. 2002. pH-dependent regulation of lysosomal calcium in macrophages. J. Cell Sci. 115: 599-607.
60.  Diakonova, M., G. Bokoch and J. A. Swanson.  2002.  Dynamics of cytoskeletal proteins during Fcg receptor-mediated phagocytosis in macrophages. Mol. Biol. Cell 13: 402-411.
61.  Glomski, I. J., M. M. Gedde, A. W. Tsang, J. A. Swanson and D. A. Portnoy.  2002. The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. J. Cell Biol. 156: 1029-1038.
62.  Grieshaber, S., J. A. Swanson and T. Hackstadt.  2002.  Determination of the physical environment within the Chlamydia trachomatis inclusion using ion-selective ratiometric probes.  Cell. Microbiol. 4: 273-283.
63.  Myers, J. T. and J. A. Swanson.  2002.  Calcium spikes in activated macrophages during Fcg receptor-mediated phagocytosis.  J. Leukoc. Biol. 72: 677-684.
64. Swanson, J. A.  2002.  The extraordinary phagosome. Nature 418: 286-287.
65. Swanson, J. A.  2002.  Ratiometric fluorescence microscopy. In: Methods in Microbiology, Molecular Cellular Microbiology. Vol. 31,  P. Sansonetti and A. Zychlynsky, eds., Academic Press, NY. pp 1-18.
66.  Hoppe, A. D., K. A. Christensen and J. A. Swanson.  2002.  Fluorescence resonance energy transfer-based stoichiometry in living cells.  Biophys. J. 83: 3652-3664. View pdf
67. Araki, N., T. Hatae, A. Furukawa and J. A. Swanson.  2003.  Phosphoinositide 3-kinase-independent contractile activities associated with Fcg receptor-mediated phagocytosis and macropinocytosis in macrophages. J. Cell Sci. 116: 247-257.
68. Saito, G., J. A. Swanson and K. -D. Lee. 2003. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: Role and site of cellular reducing activities. Adv. Drug Deliv. Revs. 55: 199-215.
69. Myers, J. T., A. W. Tsang and J. A. Swanson.  2003.  Localized reactive oxygen and nitrogen intermediates inhibit escape of Listeria monocytogenes from vacuoles in activated macrophages. J. Immunol. 171: 5447-5453.
70. Henry, R. M., A. D. Hoppe, N. Joshi and J. A. Swanson.  2004.  The uniformity of phagosome maturation in macrophages.  J. Cell Biol. 164: 185-194.
71.  Henry, R. M. and J. A. Swanson. 2004. Phagocytosis.  Encyclopedia of Molecular Cell Biology and Molecular Medicine. Wiley-VCH Verlag, Germany.
72. Hoppe, A. D. and J. A. Swanson. 2004. Cdc42, Rac1 and Rac2 display distinct patterns of activation during phagocytosis.  Mol. Biol. Cell.  15: 3509-3519. View pdf
73. Swanson, J. A. and A. D. Hoppe. 2004. The coordination of signaling during Fc receptor-mediated phagocytosis.  J. Leukoc. Biol. 76: 1093-1103. View pdf
74.      Swanson, J. A. and P. J. Peters.  2005.  Editorial Overview: Subcellular Imaging Technologies – Microscopic Visual Thinking.  Curr. Opin. Microbiol. 8: 313-315.
75. Komiyama, T, J. A. Swanson and R. S. Fuller. 2005. Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and chloroquine. Antimicrob. Agents and Chemotherapy 49: 3875-3882.
76.      Swanson, J. A. 2006.  The pick of the nibbled bits.  Nature 440: 750-751.
77. Hoppe, A. D., J. A. Swanson and S. L. Shorte. 2006. Three-dimensional FRET microscopy. Proc. of SPIE  6089: 609804-1-9.
78. Swanson, J. A. 2006. CFTR: Helping to acidify macrophage lysosomes.  Nature Cell Biol. 8: 908-909.
79. Henry, R. M., L. Shaughnessy, M. J. Loessner, C. Alberti-Segui, D. E. Higgins and J. A. Swanson.  2006.  Cytolysin-dependent delay of vacuole maturation in macrophages infected with Listeria monocytogenesCell. Microbiol. 8: 107-119. View pdf
80. Shaughnessy, L., A. D. Hoppe, K. A. Christensen and J. A. Swanson. 2006.  Membrane perforations inhibit lysosome fusion by altering pH and calcium in Listeria monocytogenes vacuoles. Cell. Microbiol. 8: 781-792. View pdf
81. Beemiller, P., A. D. Hoppe and J. A. Swanson. 2006.  A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcg receptor-mediated phagocytosis. PLoS Biology 6(4): e162. View pdf
82. Shaughnessy, L. M. and J. A. Swanson. 2007.  The role of the activated macrophage in clearing Listeria monocytogenes infection.  Frontiers Biosci. 12: 2683-2692. View pdf
83.  Walter, N.G, J.-C. Meiners, E. Meyhofer, R. R. Neubig, R. K. Sunihara, N. C. Perkins, D. G. Steel and J. A. Swanson. 2007. Under the microscope. Single molecule symposium at the University of Michigan, 2006. Biopolymers 85: 106-114.
84. Cai, D., A. D. Hoppe, J. A. Swanson and K. J. Verhey. 2007. Kinesin-1 structure and conformational changes revealed by FRET stoichiometry in live cells.  J. Cell Biol. 176: 51-63.
85. Seveau, S., T. N. Tham, B. Payrastre, A. D. Hoppe, J. A. Swanson and P. Cossart. 2007.  A FRET analysis to unravel the role of cholesterol in Rac1
and PI 3-kinase activation in the InlB/Met signalling pathway. Cell. Microbiol. 9(3): 790-803.

86. Shaughnessy, L. M., P. Lipp, K.-D. Lee and J. A. Swanson. 2007.  Localization of protein kinase C e to macrophage vacuoles perforated by Listeria monocytogenes cytolysin. Cell. Microbiol. 9(7): 1695-1704.

87. Kamen, L. A., J. Levinsohn and J. A. Swanson. 2007.  Differential localization of phosphatidylinositol 3-kinase, SHIP-1 and PTEN with forming phagosomes.  Mol. Biol. Cell.  18: 2463-2472.

88. Diakonova, M., E. Helfer, S. Seveau, J. A. Swanson, C. Kocks, L. Rui, M.-F. Carlier, and C. Carter-Su. 2007. Adapter protein SH2-Bb stimulates actin-based motility of Listeria monocytogenes in a vasodilator-stimulated phosphoprotein (VASP)-dependent fashion. Infect. Immunity. 75: 3581-3593.

89. Li, Y., Y. Wang, E. Kim, P. Beemiller, C. Y. Wang, J. Swanson, M. You and K. L. Guan. 2007. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.  J. Biol. Chem. 282: 35803-35813.

90. Kamen, L. A., J. Levinsohn, A. Cadwallader, S. Tridandapani and J. A. Swanson. 2008. SHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages.  J. Immunol. 180: 7497-7505.

91. Hoppe, A. D., S. L. Shorte, J. A. Swanson, and R. Heintzmann. 2008. 3D-FRET reconstruction microscopy for analysis of dynamic molecular interactions in live cells.  Biophys. J. 95: 400-418.

92. Swanson, J. A. 2008. Shaping cups into phagosomes and macropinosomes.  Nature Rev. Mol. Cell Biol. 9: 639-649.

93. Hoppe, A. D., S. Seveau and J. A. Swanson. 2009. Live cell fluorescence microscopy to study microbial pathogenesis.  Cell. Microbiol. 11(4): 540-550.

94.  Heinsbroek, S. E. M., L. A. Kamen, P. R. Taylor, G. D. Brown, J. Swanson and S. Gordon. 2009. Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages.  J. Innate Immun. 1: 244-253.

95. Yoshida, S., A. D. Hoppe, N. Araki and J. A. Swanson. 2009. Sequential signaling in plasma membrane domains during macropinosome formation in macrophages. J. Cell Sci. 122: 3250-3261.

96. Swanson, J. A. 2009. Signaling for Phagocytosis.  In: Phagocyte-Pathogen Interactions, D.G. Russell and S. Gordon, eds. ASM Press, Washington, D.C. pp. 195-208.


Lee, K.-D.; D. A. Portnoy & J. A. Swanson. 1997. Intracellular Delivery of Macromolecules. U. S. Patent number 5,643,599.