-Amino Acids via Chiral Isoxazolines." J. Am. Chem.
Soc. 2005, 127(15),
5376-83. [Abstract][PDF][HTML][Supporting
Info]Publications
29. Lee, L.W.; Taylor, C.E.; Desaulniers, J.P.; Zhang, M.; Højfeldt, J.W.;
Pan, Q.; Mapp, A.K. "Inhibition of ErbB2(Her2) expression with small molecule
transcription factor mimics." Bioorg Med Chem Lett 2009, 19(21), 6233-6.[PDF][HTML][Supporting
Info]
28. Majmudar, C.Y.; Lee, L.W.; Lancia, J.K.; Nwokoye, A.; Wang, Q.; Wands,
A.M.; Wang, L.; Mapp, A.K. "Impact of Nonnatural Amino Acid Mutagenesis on
the in Vivo Function and Binding Modes of a Transcriptional Activator." J. Am.
Chem. Soc. 2009, 131(40), 14240-2. [Abstract][PDF][HTML][Supporting
Info]
27. Majmudar, C.Y.; Wang, B.; Lum, J.K.; Håkansson, K.; Mapp, A.K. "A
High-Resolution Interaction Map of Three Transcriptional Activation Domains with
a Key Coactivator from Photo-Cross-Linking and Multiplexed Mass Spectrometry."
Angew. Chem. Intl. Ed. Engl. 2009, 48 (38), 7021-7024. [Abstract][PDF][HTML][Supporting
Info]
26. Bao, L.; Gorin, M.A.; Zhang, M.; Ventura, A.C.; Pomerantz, W.C.; Merajver, S.D.; Teknos, T.N.; Mapp, A.K.; Pan, Q. "Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer." Cancer Res. 2009, 69(14), 5829-34. [Abstract][PDF][HTML]
25. Majmudar, C.Y.; Labut, A.E.; Mapp, A.K. "Tra1 as a screening target for transcriptional activation domain discovery." Bioorg. Med, Chem. Lett. 2009, 19(14), 3733-5. [Abstract][PDF][HTML]
24. Aminoff, D.; Bochar, D.A.; Fuller, A.A.; Mapp, A.K.; Showalter, H.D.; Kirchhoff, P.D. "Research into slective biomarkers of erythrocyte exposure to organophosphorus compounds." Anal Biochem. 2009, 392(2), 155-61. [PDF][HTML]
23. Buhrlage, S.J.; Bates, C.A.; Rowe, S.P.; Minter, A.R.; Brennan, B.B.; Majmudar, C.Y.; Wemmer, D.E.; Al-Hashimi, H. M.; Mapp, A.K. "Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors." ACS Chem Biol, 2009, 4(5), 335-344. [Abstract][PDF]
22. Buhrlage, S.J.; Chen, B.; Mapp, A.K. "A flexible synthetic route to isoxazolidine b-proline analogs." Tetraherdon, 2009, 65 (16), 3305-3313. [PDF]
21. Rowe, S.P.; Mapp, A.K. "Assessing the permissiveness of transcriptional activator binding sites." Biopolymers, 2008, 89 (7), 578-581. [PDF]
20. Casey, R. J.; Desaulniers, J.-P.; Hojfeldt, J. W.; Mapp, A.K. "Expanding the repertoire of small molecule transcriptional activation domains." Bioorg. Med. Chem. 2009, 17 (3), 1034-1043. [PDF][HTML]
19. Rowe, S.P.; Casey, R.J.; Brennan, B.B.; Buhrlage, S.J.; Mapp, A.K.
"Transcriptional Up-regulation in Cells Mediated by a Small Molecule"
J. Am. Chem. Soc. 2007,
129 (
18. Lum, J.K.; Wu, Z.; Mapp, A.K. "Disrupting Mediator with a Short Peptide Ligand." ChemBioChem. 2007, 8(11),1233-1236. [Abstract][PDF][HTML]
17. Mapp, A.K.; Ansari, A.Z. "A TAD further: exogenous control of gene activation." ACS Chem Biol. 2007, 2(1), 62-75. [Abstract][PDF][HTML]
16. Lum, J.K.; Majmudar, C.Y.; Ansari, A.Z.; Mapp, A.K. "Converting
Inactive Peptides into Potent Transcriptional Activators. "
ACS Chem. Biol.
2006, 1(10), 639-643. [Abstract][PDF][HTML][Supporting
Info]
15. Ferguson, M.L;
Senecal, T.D; Groendyke, T.M.; Mapp A.K."[3,3]-Rearrangements of Phosphonium Ylides." J. Am.
Chem. Soc. 2006, 128(14),
4576-4577. [Abstract][PDF][HTML][Supporting
Info]
14. Majmudar, C.Y.; Mapp, A.K. "Chemical approaches to transcriptional regulation." Curr Opin Chem Biol. 2005, 9(5), 467-74. [Abstract][PDF][HTML]
13. Buhrlage, S.J; Brennan, B.B; Minter, A.R; Mapp, A.K. "Stereochemical promiscuity in artificial transcriptional activators." J. Am. Chem. Soc. 2005, 127(36), 12456-57. [Abstract][PDF][HTML][Supporting Info]
12. Lum, J. K.; Mapp, A. K. "Artificial Transcriptional Activation Domains." ChemBioChem. 2005, 6(8), 1311-15. [Abstract][PDF][HTML]
11. Lu, Z.; Rowe S. P.; Brennan, B. B.; Davis, S. E.; Metzler, R. E.; Nau, J. J.; Majmudar, C.Y.; Mapp, A. K.; Ansari, A. Z. "Unraveling the mechanism of a potent transcriptional activator" J. Biol. Chem. 2005, 280(33), 29689-98. [Abstract][PDF][HTML][Supporting Info]
10. Chen, B.; Mapp, A. K.
"Thermal and Catalyzed [3,3]-Phosphorimidate
Rearrangements."
J. Am. Chem. Soc. 2005, 127(18), 6712 - 18.
[Abstract][PDF][HTML][Supporting
Info]
9. Majmudar, C. Y.; Lum, J. K.; Prasov, L.; Mapp, A.K. "Functional Specificity of Artificial Transcriptional Activators." Chem. Biol. 2005, 12, 313-21. [Abstract][PDF][HTML][Supporting Info][Preview-Abstract][Preview-PDF]
8. Fuller, A. A.; Chen, B.; Minter A. R.; Mapp, A. K.
"Succinct Synthesis of -Amino Acids via Chiral Isoxazolines." J. Am. Chem.
Soc. 2005, 127(15),
5376-83. [Abstract][PDF][HTML][Supporting
Info]
7. Minter, A. R.; Brennan, B.B.; Mapp, A.K. "Small molecule artificial transcriptional activation domains." J. Am. Chem. Soc. 2004, 126, 10504-5. [Abstract][PDF][HTML][Supporting Info]
6. Fuller, A.A.; Chen, B.; Minter, A.R.; Mapp, A.K. "Synthesis and structural features of geminally disubstituted β-amino acids." Synlett, 2004, 1409-10.[PDF][HTML]
5. Chen, B.; Mapp, A. K.
"A
Phosphorimidate Rearrangement for the Facile and Selective Preparation of
Allylic Amines."
J. Am. Chem. Soc.
2004,
126(17), 5364-5.[Abstract][PDF][HTML][Supporting
Info]
4. Wu, Z.; Belanger, G.; Brennan, B. B.; Lum, J. K.; Minter, A. R.; Rowe, S. P.; Plachetka, A.; Majmudar, C. Y.; Mapp, AK. "Targeting the Transcriptional Machinery with Unique Artificial Transcriptional Activators." J. Am. Chem. Soc. 2003, 125, 12390-1. [Abstract] [PDF][HTML][Supporting Info]
3. Minter AR, Fuller AA, Mapp AK. "A Concise Approach to Structurally Diverse beta-Amino Acids." J. Am. Chem. Soc. 2003, 125(23), 6846-7. [Abstract][PDF][HTML][Supporting Info]
2. Mapp, AK. "Regulating transcription: A Chemical Perspective." Org. Biomol. Chem., 2003, 1 (13), 2217-20. [Abstract] [Full Text]
1. Ansari
AZ, Mapp AK. "Modular design of artificial transcription
factors." Curr Opin Chem
Biol. 2002, 6(6), 765-72. Review. [Abstract]
[PDF]
This page was last modified on 11/09/09 .