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From Microscopic to Macroscopic – Mechanisms Underlying Epileptic Seizures |
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May 8 -10, 2007 Located at the Palmer Commons, Forum Hall 100 Washtenaw Ave, 4th floor University of Michigan, Ann Arbor, Central Campus
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Epilepsy is a dynamical disease of the brain that affects 2% of the US population and is epitomized by bursts of indiscriminate synchronous activity affecting large neuronal populations. Significant experimental and theoretical research has focused on elucidating the molecular, cellular and network mechanisms underlying seizure generation and progression. Other work, much of it computational, has focused on the development of tools for predicting and controlling seizures. Despite the broad range of experimental and theoretical work on epilepsy, little has been done to integrate studies at different length scales into a coherent framework. The aims of this workshop are to promote an understanding of the relationships among studies at multiple scales, to spur the development of a common framework relating experimental and theoretical/modeling efforts, and to generate new kinds of questions and new research initiatives. The external invited participants in this workshop, drawn from many diverse fields in the physical and biological sciences, represent a wide range of experimental and theoretical scientists studying epilepsy at the molecular, cellular and systems levels.
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