|
. .  
|
Faculty
Research InterestsMy aims are (1) to stimulate productive research relationships between biological and clinical scientists and counterparts in computational, mathematical, and statistical disciplines; and (2) to discover, validate, and apply protein biomarkers for early diagnosis and for exploration of pathways and targets for treatment of lung and prostate cancers, employing proteomics and informatics approaches. Under the National Center for Integrative Biomedical Informatics (www.ncibi.org) we study and model prostate cancer progression, type 1 diabetes complications, and the genotypic heterogeneity of type 2 diabetes and bipoloar disease with novel computational tools and deep integration methods. Under the Proteomics Alliance for Cancer (Michigan Life Sciences Corridor), we pursue new technology, study human tumor and cell line specimens, and develop databases for the findings. We have the lead role for the Human Proteome Organization international collaboration on the HUPO Plasma Proteome Project. Extensive findings from the Pilot Phase were published in August 2005 in a special issue of Proteomics entitled "Exploring the Human Plasma Proteome". This work provides a foundation for studies of variation across populations and sub-populations, and within individuals over time due to physiological, pathological, and pharmacological perturbations. Education1958 Chester High School, Chester, PA 1961 Princeton University, Princeton, NJ, A.B., summa cum laude 1965 Harvard Medical School, Boston, MA, M.D., magna cum laude 1972 University of Washington, Seattle, WA, Ph.D. (genetics) Postgraduate Training1960 Research Fellow, Woods Hole Oceanographic Institute, Woods Hole, MA 1961 Research Fellow, Brookhaven National Laboratory, Upton, L.I., NY 1962 Research Fellow, Weizmann Institute of Science, Rehovot, Israel 1962-65 Harvard Medical School, Boston, MA, M.D. Thesis Program 1965-67 Intern, Assistant Resident in Medicine, Massachusetts General Hospital, Boston, MA 1966-67 Teaching Fellow in Medicine, Harvard University, Boston, MA 1967-69 Research Associate, National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, MD 1969-71 Fellow, Division of Medical Genetics, University of Washington, Seattle, WA Faculty and Related Positions: 1971-74 Assistant Professor of Medicine (Medical Genetics), University of Washington, Seattle, WA 1971-97 Attending Staff, University Hospital, Harborview Medical Center, Veterans Administration, Hospital, Providence Hospital; Consulting Staff, Children's Hospital and Medical Center, Seattle, WA 1973-74 White House Fellow and Special Assistant to Chair, Atomic Energy Commission, Washington, DC, and Germantown, MD 1974-79Associate Professor of Medicine (Medical Genetics), University of Washington, Seattle, WA 1975-77 Director, Robert Wood Johnson Clinical Scholars Program at the University of Washington, Seattle, WA 1976-77 Investigator, Howard Hughes Medical Institute 1977-80 Assistant Director (1977-78), Associate Director (1978-80) for Human Resources and Social and Economic Services, Office of Science and Technology Policy, Executive Office of the President, Washington, DC 1979-97 Professor of Medicine (Medical Genetics), University of Washington, Seattle, WA 1980-81 Associate Director for Human Resources, Veterans and Labor, Office of Management and Budget, Executive Office of the President, Washington, DC 1981 Visiting Senior Fellow, Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ 1981-82 Science and Public Policy Fellow, Brookings Institution, Washington, DC 1981 Professor of Environmental Health, University of Washington, Seattle, WA; Affiliate Prof 9/97-- 1982-83 Chair, Department of Environmental Health, University of Washington, Seattle, WA 1982-97 Dean, School of Public Health and Community Medicine, University of Washington, Seattle, WA; Dean Emeritus, 1997 1983 Member (joint), Fred Hutchinson Cancer Research Center, Seattle, WA (affiliate, 1997--) 1997-2002 Executive Vice President for Medical Affairs, CEO of University of Michigan Health System, Ann Arbor, MI 1997-present Professor of Internal Medicine, Human Genetics and Public Health, University of Michigan, Ann Arbor, MI Honors and Awards1969-71 U.S. Public Health Service Special Fellow 1971-72 National Genetics Foundation Fellow 1972-76 Research Career Development Award, National Institute of General Medical Sciences 1973-74 White House Fellow, Atomic Energy Commission, Germantown, MD 1978 Fellow, American College of Physicians 1978 Member, Institute of Medicine, National Academy of Sciences 1981 Fellow, Hastings Center Institute of Society, Ethics and Life Sciences 1985 Fellow, Collegium Ramazzini 1991 Fellow, American Association for the Advancement of Science 1991 Member, National Academy of Social Insurance 1992 Member, Western Association of Physicians 2001 Member, American Academy of Arts and Sciences 2001 Member, Association of American Physicians 2004-2007 President-Elect, President, Chairman, American Assn for the Advancement of Science (AAAS) 2004 President’s Award, American Occupational Medicine Association 2004 John W. Gardner Legacy of Leadership Award, White House Fellows Assn
|
||||||
|
|||||||
