Advanced Raman Microscopy & Chemical Imaging Lab

 

Recent publications

Papers in refereed journals.

  1. Kohn, David H.; Sahar, Nadder D.; Wallace, Joseph M.; Golcuk; Kurtulus; Morris, Michael D. Exercise alters mineral and matrix composition in the absence of adding new bone, Cells, Tiss., Organs 2008, 189, 33-37. (link)

  2. Schulmerich, Matthew V.; Srinivasan, Subhadra; Cole, Jacqueline H.; Kreider, Jaclynn; Dooley, Kathryn A;. Goldstein; Steven A.; Pogue, Brian W.; Morris, Michael D. Non-invasive Raman tomographic imaging of canine cortical bone tissue, J. Biomed. Optics, 2008, 13(2), 020506. (link)

  3. Esmonde-White, Karen A.; Le Clair Stephanie V.; Roessler, Blake J.; Morris, Michael D. Effect of Conformation and Drop Properties on Surface-Enhanced Raman Spectroscopy of Dried Biopolymer Drops Appl. Spectrosc. 2008, 62, in press.

  4. Schulmerich, Matthew V.; Cole, Jacqueline H.; Dooley, Kathryn A;. Kreider, Jaclynn M.; Goldstein;Steven A.; Morris, Michael D. Optical clearing in transcutaneous Raman spectroscopy of bone tissue , J. Biomed. Optics, 2008, 13,021108. (link)

  5. Levina, E.; Wagaman, A.S.; Callender, A.F.; Mandair, G.S.; Morris, M.D., Estimating the number of pure chemical components in a mixture by maximum likelihood, J. Chemomet. 2007, 21, 24-34. (link)

  6. Schulmerich, Matthew V.; Dooley, Kathryn A.; Vanasse, Thomas M.; Goldstein, Steven A.; Morris, Michael D. Subsurface and Transcutaneous Raman Spectroscopy and Mapping using Concentric Illumination Rings and Collection with a Circular Fiber Optic Array, Appl. Spectrosc. 2007, 61, 671-678. (link)

  7. Awonusi, Ayorinde ; Morris, Michael D.; Tecklenburg; Mary M. J. , Carbonate Assignment and Calibration in the Raman Spectrum of Apatite, Calcif. Tissue Internat. 2007, 61, 671-678.

  8. McCreadie, Barbara R., Morris, Michael D., Chen, Tso-Ching, Sudhaker Rao, D., Finney, William F., Widjaja, Effendi, and Goldstein, Steven A. (2006). Bone tissue compositional differences in women with and without osteoporotic fracture. Bone 2006, 39, 1190-1195. (link)

  9. Schulmerich, Matthew V.; Dooley, Kathyrn A.; Morris, Michael D.; Vanasse, Thomas M.; Goldstein, Steven A. Transcutaneous fiber optic Raman spectroscopy of bone using annular illumination and a circular array of collection fibers, J. Biomed. Optics 2006, 11, 060502. (link)

  10. Dehring, Karen A.; Crane, Nicole J.; Smukler, Abigail R.; McHugh, Jonathan, Roessler, Blake J.; Morris, Michael D. Identifying Chemical Changes in Subchondral Bone Taken from Murine Knee Joints Using Raman Spectroscopy, Appl. Spectrosc. 2006, 60, 1134-1141. (link)

  11. Morris, Michael D.; Roessler, Blake J., Future spectroscopic diagnostics in osteoarthritis, Fut. Rheumatol. 2006, 1, 383-386. (link)

  12. Wilson, Erin E; Awonusi, Ayorinde; Morris, Michael D; Kohn,David H; Tecklenburg, Mary MJ; Beck; Larry W. Three Structural Roles for Water in Bone Observed by Solid-State NMR, Biophys. J. 2006, 90, 3722-3731. (link)

  13. Golcuk, Kurtulus; Mandair, Gurjit S.; Callender, Andrew F. Sahar, Nadder; Kohn, David H.; Morris, Michael D Is photobleaching necessary for Raman imaging of bone tissue using a green laser?, Biochim. Biophys. Acta 2006, 1758, 868-873. (link)

  14. Finney, William F.; Wilson, Erin; Callender, Andrew; Morris, Michael D.; Beck Larry W. Reexamination of Hexafluorosilicate Hydrolysis by 19F NMR and pH Measurement, Environ. Sci. Technol. 2006, 40, 2572-2577. (link)

  15. Fenniri, Hicham; Terreau, Owen; Chun, Sangki; Oh, Sung Joon; Finney, William F.; Morris, Michael D. Classification of Spectroscopically Encoded Resins by Raman Mapping and Infrared Hyperspectral Imaging, J. Comb. Chem. 2006, 8, 192-198. (link)

Book chapters

  1. Morris, M.D.; Mandair G.S.; Biomedical Applications of Raman Imaging, in Raman, Infrared and Near-infrared Chemical Imaging, edited by Ozaki, Y and Slobodan, S., Wiley, (submitted, 2009)

  2. Morris, Michael D.; Schulmerich, Matthew V.; Dooley, Kathryn A.; Esmonde-White, Karen, Vibrational Spectroscopic Imaging of Hard Tissue, in Infrared and Raman Spectroscopic Imaging, edited by R. Salzer and H. W. Siesler, Wiley-VCH, in press.

Proceedings from conferences and symposia.

  1. Mandair, G.S.; Bateman, T.A.; Morris, M.D.; Raman spectroscopy of murine bone in response to simulated spaceflight conditions. Proc. SPIE., 2009, 7166 (link)

  2. Cole, J.H.; Waldorff, E.I.; Rudoni, M.A.; Goldstein, S.A.; Morris, M.D., Microdamage assessment in rat cortical bone by light scattering, Trans Orthop Res Soc 2008, 33:138.

  3. Cole, J.H.; Schulmerich, M.V.; Dooley, K.A.; Kreider, J.M.; Daley, E.; Goldstein, S.A.; Morris, M.D., Measurement protocols for the non-invasive assessment of bone constituent properties by Raman spectroscopy, J Bone Miner Res 2007, 22(Suppl 1): T108.

  4. Schulmerich, M. V. Srinivasan, S.; Krieder, J.; Cole, J. H., Dooley, K. A.; Goldstein, S.A., Pogue, B. W.; Morris, M. D., Raman tomography in tissue phantoms and tissue, Proc. SPIE 2008, 6853, 68530V

  5. Raghavan, M.; Morris, M.D.;Sahar, N.; Kohn, D.H. Polarization Raman spectroscopy: application to biomechanics, Proc. SPIE 2008, 6853, 68530W.

  6. Esmonde-White, K. A.; Mandair, G. S.; LeClair, S.; Raaii, F.; Roessler, B. J.; Morris, M.D. Raman Spectroscopy of Dried Synovial Fluid Droplets as a Rapid Diagnostic for Knee Joint Damage, Proc. SPIE 2008, 6853, 68530Y.

  7. Dooley, K.A.; McCormack, J.; Fyhrie, D.P.; Morris, M.D. Compositional differences among undamaged, strained and failed regions of bone using Raman spectroscopy. Proc. SPIE 2008, 6853, 68530Z

  8. Morris, Michael D. Spatially offset Raman spectroscopy and diffuse Raman tomography: subsurface spectroscopy and imaging in animal tissue and other scattering media, Proc. SPIE 2008, 6853, 68530I.

  9. Esmonde-White, Karen A.; Mandair, Gurjit S.; Roessler, Blake J.; Morris, Michael D., Surface-Enhanced Raman Spectroscopy Detection of Hyaluronic Acid: A Potential Biomarker for Osteoarthritis, in New Approaches in Biomedical Spectroscopy, Kneipp, Katrin ; Aroca, Ricardo; Kneipp, Harald and Wentrup-Byrne, Edeline, Eds. Oxford University Press, Washington, 2007, pp. 123-137.

  10. Iwen, M.A.; Mandair, G.S.; Morris, M.D.; Strauss, M.; Fast Line-Based Imaging of Small Sample Features. IEEE Conference., 2007;1:I421-4

  11. Golcuk, Kurtulus; Vanasse, Thomas M.; Morris, Michael D.; Goldstein, Nanometer tracking of single quantum dot array fluorescence: application to bone biomechanics, Proc. SPIE 2007, 6448, 644815.

  12. Dehring, Karen A.; Roessler, Blake J.; Morris, Michael D. Correlating chemical changes in subchondral bone mineral due to aging or defective type II collagen by Raman spectroscopy. Proc. SPIE 2007, 6430,64301B.

  13. Schulmerich, Matthew V.; Morris, Michael D.; Vanasse, Thomas M.; Goldstein, Steven A. Transcutaneous Raman spectroscopy of bone global sampling and ring/disk fiber optic probes, Proc. SPIE 2007, 6430, 643009.

  14. Golcuk, K.; Mandair, G.S.; Callender, A.F.; Finney, W.F.; Sahar, N.; Kohn, D.H., Morris, M.D., Rapid Raman spectroscopy of musculoskeletal tissue using a visible laser and an electron-multiplying CCD (EMCCD) detector, Proc.SPIE 2006, 6093, 609314.

  15. Mandair, Gurjit S.; Dehring, Karen A.; Roessler, Blake J.; Morris, Michael D. Detection of Potential Osteoarthritis Biomarkers using Surface-Enhanced Raman Spectroscopy in the Near-Infrared, Proc. SPIE 2006, 6093, 60930H.

  16. Morris, M.D.; Schulmerich, M.V.; Finney, W.F.; Goldstein S.A.; Vanasse, T.M., Transcutaneous Raman spectroscopy of bone tissue using a non-confocal fiber optic array probe, Proc. SPIE 2006, 6093, 609314.