Kate F Barald Ph.D.
| 3053 BSRB 2200 |
| Ann Arbor, MI 48109 |
Download this page 
The laboratory focuses on the development of the inner ear and its innervation and regeneration. We are interested in the developmental gene expression that results in a functional three-dimensional inner ear.
We are also interested in the development of neurogenic lineages from the neural crest, a transient embryonic migratory cell population that gives rise to the majority of cells in the peripheral nervous system. We are investigating the role of the neurofibromatosis 1 gene in the development of neurons and Schwann cells, using an embryonic stem cell model.
Bianchi, L.M., Daruwalla, Z., Richards, A.-L., Roth, T.M., Attia, N., Lukacs, N.W., White, I.O., Allen, S.J. and Barald, K. F. (2005). Immortalized mouse inner ear cell lines demonstrate a role for chemokines in promoting the growth of developing statoacoustic ganglion neurons. JARO, 6: 355 - 367. Germiller, JA, Smiley, E, Allen, SJ, Hoff, J, Deshmukh, I and Barald, KF. Immortalized inner ear cell models of the developing otocyst. Dev. Dynamics 231: 815-827
Barald, KF and Kelley, MW (2004). From Placode to Polarization: New Tunes in Development of the Inner Ear.‚Äö Development, 131: 4119-4130.
Doudou, E., Barald, K.F. and Postlethwait, J.H. (2004). Over-expression of Zic2a rescues ventralized zebrafish embryos. Zebrafish 1: 239-257.
Gerlach-Bank, LM, Cleveland, AR and Barald, KF (2004). DAN directs endolymphatic sac and duct outgrowth in the avian inner ear.‚Äö Developmental Dynamics. 229: 219-230.
Warner, SJ, Hutson, MH, Oh, S-H, Gerlach-Bank, LM, Lomax, MI and Barald, KF (2003). Expression of ZIC Genes in the Development of the Chick Inner Ear and Nervous System. Dev. Dyn. 226: 702-712.
Thompson, D, Gerlach-Bank, LM, Barald, KF and Koenig, RJ (2003). Retinoic Acid Repression of BMP4 in Inner Ear Development.‚Äö Molecular‚Äö and Cellular Biology.‚Äö 23: 2277-2286.
Gerlach-Bank, LM, Ellis, AD, Noonen, B and Barald, KF (2002).‚Äö Cloning and expression analysis of the chick DAN gene, an antagonist of the BMP family of growth factors.‚Äö Dev. Dynam. 224: 109-115.
Gerlach, LM, Hutson, MR, Germiller, JA, Nguyen-Luu, D. and Barald, KF (2000) Addition of the BMP4 antagonist, noggin disrupts avian inner ear development. Development,‚Äö 127: 45-54. (published on the web, Dec. 8, 1999)
Hutson, M. R., Lewis, J.E., Nguyen-Luu, Lindberg, K.H. and Barald, K.F. (1999) Expression of Pax-2 and patterning of chick inner ear. J. Neurocytol. 28,795-807.
Lumeng, C. Phelps, S., Crawford, G.E., Hutchinson, T., Walden, P.D., Barald, K. and Chamberlain, J.S. (1999) Interactions between B2-syntrophin and a family of microtubule associated serine/threonine kinases. Nature Neuroscience, 2 611-7.
Find more publications by Dr.Kate Barald