Karley Little M.D.
| 116-A VA Medical Center 2399 |
| Ann Arbor, MI 48109 |
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Our laboratory studies the biochemistry and pharmacology of monoamine synaptic transporters, particularly in relationship to altered mood and reward.
Little, K.Y., Carroll, F.I., Butts, J.D.: Striatal [125I]RTI-55 binding sites in cocaine-abusing humans, Prog. Neuro-Psychopharmacology & Biol. Psychiatry 22:455-466, 1998.
Duncan, G.E., Knapp, D.J., Breese, G.R., Crews, F.T., Little, K.Y.: Species differences in regional patterns of 3H-8-OH-DPAT and 3H-zolpidem binding in the rat and human brain. Pharmac. Biochem. Behav. 60:439-48, 1998.
Zhang, L., Elmer, L.W., Little, K.Y.: Expression and regulation of the human dopamine transporter in a neuronal cell line. Molec. Brain. Research. 59:66-73, 1998
Mitsuyama, H., Little, K.Y., Sieghart, W., Fritschy, J.-M., Devaud, L.L., Morrow, A.L.: GABAA receptor a1, a4, and b3 subunit mRNA and protein expression in frontal cortex of human alcoholics. Alcoholism: Clinical and Experimental Research 22:815-22, 1998.
Little, K.Y. Zhang, L., Desmond, T., Frey, K.A., DalackG.W., Cassin, B.J.: Striatal dopaminergic alterations in human cocaine users. Am. J. Psychiatry. 156:238-245, 1999.
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