Jeffrey R Martens Ph.D.
| 1301 MSRB III |
| Ann Arbor, MI 48109 |
Download this page 
My research is focused on characterizing the role of protein-lipid interactions in ion channel targeting and function with an emphasis on understanding the details of K+ channel/lipid interactions and how this is integrated into the broader context of normal cellular signaling and the pathogenesis of disease.
Brainard AM, Miller AJ, Martens JR, England SK: Localization of Maxi-K channels to Caveolae in Human Myometrium: A role for an Actin-Channel-Caveolin Complex in the Regulation of Myometrial Smooth Muscle K+ Current. J. Biol. Chem. 2004; submited
O’Connell K, Martens JR, Tamkun MM: Localization of Ion channels to Lipid Raft Domains within the Cardiovascular System. Trends Cardiovasc Med. 2004 Feb;14(2):37-42
Martens JR, O’Connell K, Tamkun MM: Targeting of Ion Channels to Membrane Microdomains: Localization of Kv Channels to Lipid Rafts. Trends Pharm. Sci. 2004; 25(1):16-21
Brady JD, Rich TC, Le X, Stafford K, Fowler CJ, Lynch L, Karpen JW, Brown RL, Martens JR: Functional Role of Lipid Raft Microdomains in Cyclic Nucleotide-Gated Channel Activation. Mol. Pharm. 2004; 65(3):503-511
Fergus DJ, Martens JR, England SK: Kv Channel Subunits that Contribute to Voltage-gated K+ Current in Renal Vascular Smooth Muscle. Pflugers Archives. 2003; 445(6):697-704
Martens JR, Sakamoto N, Sullivan SA, Grobaski TD, Tamkun MM: Isoform Specific Localization of Voltage-gated K+ Channels to Distinct Lipid Raft Populations: Targeting of Kv1.5 to Caveolae. J. Biol. Chem. 2001;276:8409-8414
Coppock EA, Martens JR, Tamkun MM: Molecular Basis of Hypoxia-induced Pulmonary Vasoconstriction - Role of Voltage-gated K+ Channels. Am. J. Physiol Lung Cell Mol Physiol. 2001;281(1):L1-12
Martens JR, Kwak YG, Tamkun MM: Modulation of Kv Channel a/b Subunit Interactions. Trends Cardiovascular Med. 1999; 9(8):253-258
Hulme JT, Martens JR, Navarro R, and Tamkun MM: Voltage-gated K+ channels in the myocardium. In Potassium Channels in Cardiovascular Biology (Archer, S.L. and Rusch, N.J., eds.) Plenum Publishing, New York 2001;pp 337-362
Martens JR, Navarro-Polanco R, Coppock EA, Nishiyama A, Parshley L, Grobaski TD, Tamkun MM: Differential Targeting of Shaker-like Potassium Channels to Lipid Rafts. J. Biol. Chem. 2000; 275:7443-7446
Find more publications by Dr.Jeffrey Martens