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Syllabus
for EEB 401: Evolution and Development, Winter 2007, section 001 |
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Instructor:
Dr. Trisha
Wittkopp (wittkopp@umich.edu, 1061 Natural Science Building) |
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Where:
120 Denniston |
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When: T Th 2:30-4:00 |
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Textbook:
From DNA to
Diversity: Molecular genetics and the Evolution of animal design, 2nd ed |
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by S.B.
Carroll, J.K. Grenier, and S.D. Weatherbee (Blackwell publishing) |
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Day |
Date |
Class |
Topic |
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Reading |
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Th |
4-Jan |
1 |
Course
policies, survey, introduction |
Paper
set 1 |
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T |
9-Jan |
2 |
A brief
history of animals |
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Preface,Ch.
1 |
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Th |
11-Jan |
3 |
Birth
of "evo-devo" (Q) |
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Paper
set 2 |
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T |
16-Jan |
4 |
The
genetic toolkit for development (P) |
Ch. 2 |
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Th |
18-Jan |
5 |
Building
animals (Q) |
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Ch. 3 |
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T |
23-Jan |
6 |
Evolution
of the toolkit |
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Ch. 4 |
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Th |
25-Jan |
7 |
Evolution
of the toolkit: Case studies (Q) |
Paper
set 3 |
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T |
30-Jan |
8 |
Diversification
of body plans |
Ch. 5 |
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Th |
1-Feb |
9 |
Diversification
of body plans: Case studies (Q) |
Paper
set 4 |
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T |
6-Feb |
10 |
Evolution
of Morphological novelties |
Ch. 6 |
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Th |
8-Feb |
11 |
Evolution
of Morphological novelties: Case studies (Q) |
Paper
set 5 |
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T |
13-Feb |
12 |
Morphological
variation and species divergence |
Ch. 7 |
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Th |
15-Feb |
13 |
Morphological
variation: Case studies (Q) |
Paper
set 6 |
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T |
20-Feb |
14 |
The
primacy of regulatory evolution (P) |
Ch. 8 |
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Th |
22-Feb |
15 |
Stabilizing
selection (Q) |
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Paper
set 7 |
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SPRING BREAK |
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T |
6-Mar |
16 |
Genetic
basis of expression differences (Q) |
Paper
set 8 |
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Th |
8-Mar |
17 |
Evolution
of sex in nematodes (Soochin Cho) |
Paper
set 9 |
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T |
13-Mar |
18 |
Mechanisms
of regulatory divergence (Q) |
Paper
set 10 |
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Th |
15-Mar |
19 |
Regressive
evolution in fish (Ted Allison) |
Paper
set 11 |
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T |
20-Mar |
20 |
Canalization
and developmental buffering (Q) |
Paper
set 12 |
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Th |
22-Mar |
21 |
Developmental
System Drift (Q) |
Paper
set 13 |
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T |
27-Mar |
22 |
Developmental
Constraints (Q) |
Paper
set 14 |
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Th |
29-Mar |
Student
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Plant
evolution: maize domestication, floral diversity |
Paper
set 15 |
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T |
3-Apr |
Student
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*Structural
modifications: finch beaks, horned beetles |
Paper
set 16 |
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Th |
5-Apr |
Student
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*Pigmentation
evolution: mouse, zebrafish |
Paper
set 17 |
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T |
10-Apr |
Student
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Evolution
of Drosophila hairs: larval, adult leg |
Paper
set 18 |
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Th |
12-Apr |
Student
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Regulatory
mechanisms: endo16, hoxc8 |
Paper
set 19 |
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T |
17-Apr |
23 |
Final
discussion: Future of Evo-Devo |
Paper
set 20 |
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F |
20-Apr |
(Graduate
students) News and Views papers due
at 5pm |
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(Q) = questions to be answered prior to class, (P) = questions/answers to be posted to the website
Course
Objectives:
The goal for this course is to introduce you to the field of evolution and
development (Òevo-devoÓ), while improving the critical thinking skills needed to
become an independent scientist. At the end of the course, you should
be familiar with the experimental approaches used to study the developmental
basis of evolutionary change as well as the Òbig pictureÓ questions that these
studies can address. Emphasis is placed on critical evaluation and synthesis of
the primary literature. Developing and expressing scientific opinions will be
stressed equally with data interpretation and experimental design.
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Expectations
for students: |
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1.
Complete reading assignment prior to class. |
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2. Type
answers to questions (Q) and bring printed copy to class. |
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3.
Post questions/answers when required. |
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4.
Participate in class discussions. |
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5. In class, either correct or add to your answers to (Q) based on
the discussion. |
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6.
Participate in group presentations at the end of the semester. |
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7.
Graduate students will write a "news and views" paper at the end of
the semester. |
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Point
distribution |
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Graduate |
Undergraduate |
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Weekly
questions |
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100 |
100 |
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Questions
for presenters |
20 |
20 |
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Posted questions/answers |
10 |
10 |
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Class
participation |
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30 |
30 |
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Group
presentation |
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50 |
50 |
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News
and views paper |
50 |
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Total |
260 points |
210 points |
Assignments and grading criteria
are described here.
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Grading
scale |
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100-97 |
A+ |
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96-92 |
A |
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91-90 |
A- |
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89-87 |
B+ |
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86-82 |
B |
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81-80 |
B- |
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79-77 |
C+ |
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76-72 |
C |
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70-71 |
C- |
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69-60 |
D |
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<60 |
E |
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Rounding:
96.5 = 97, 96.4999999 = 96 |
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