Group Members

Current Members

Metallopeptide Project

Melissa Zastrow | PhD | E-mail
Undergraduate Institution: University of Connecticut
Research Interests: Metalloenzymes



Jefferson Plegaria | PhD Candidate| E-mail
Undergraduate Institution: La Salle University
Research Interests: Solution Structure, Protein Design, Cupredoxins and Electron Transfer

Leela Ruckthong | PhD Candidate | E-mail
Undergraduate Institution: Kasetart University (Bangkok, Thailand)
Research Interests: Alternative amino acids

Fangting Yu | PhD Candidate| E-mail
Undergraduate Institution: Peking University
Research Interests: I received my B. S. in Chemistry from Peking University, China, where I worked on studying the influence of metal ions on the solubility of cholesterol in the aggregates of phospholipids and bile salts. My current research focuses on creating a De Novo designed metallopeptide as a mimic for a Type II copper center, which could potentially act as an oxygen-activating center. I also work on synthesizing dinuclear manganese complex to mimic the oxygen-evolving center in photosystem II.

Ginny Cangelosi |Post-Doc| E-mail
Undergraduate Institution: Albion College
PhD Insitution: Unversity of Oregon (Dr. Darren W. Johnson)
Research Interests: I received my BA from Albion College in 2005 and my Ph. D. in chemistry from the University of Oregon in 2010. Under the direct from Dr. Darren W. Johnson, I studied supermolecular chemistry of the Group 15 ions as an NSF GK12 fellow. My research interests include protein design, self-assembly and heavy-metal toxicity.

Cathy Mocny | PhD Candidate| E-mail
Undergraduate Institution: Kalamazoo College
Research Interests: I am interested in the interface of inorganic chemistry and biology and the roles inorganic elements play in biology. Currently I am working on synthesizing a heteromeric three stranded coiled-coil using both bio-organic and bio-inorganic approaches in attempt to construct an asymmetrical metal-binding site.

Alison Tebo | PhD Candidate | E-mail
Undergraduate Institution: University of California, Los Angeles
Research Interests: metals in biology, electron transfer and redox reactions, design of electron transfer and metalloproteins. I am currently working on designing an rubredoxin-type electron transfer protein based on a well-characterized, designed scaffold, a3DIV.

Hira Qayyum | Graduate Student | E-mail
Undergraduate Institution: University of Akron
Research Interests: My research interest is the de novo design of vanadium haloperoxidases

Andrew Hunt | Rotation Student| E-mail
Undergraduate Institution: Kent State University
Research Interests: Bioinorganic chemistry, redox active metalloproteins and the design of corresponding model systems, reactive oxygen/nitrogen species (ROS/RNS)

Daniel Lorenz | Rotation Studen | E-mail
Undergraduate Institution: Sonoma State University
Research Interests: Bioinorganic chemistry and protein design

Sara Caruso | Undergraduate | E-mail
Undergraduate Institution: University of Michigan, Ann Arbor
Research Interests: Bioinorganic chemistry and protein design
Other Interests: Running, kayaking, swimming and playing the accordion

Andrew Liu | Undergraduate | E-mail
Undergraduate Institution: University of Michigan, Ann Arbor
Research Interests: De novo designed metallopeptides, studying the effects of nearby amino acid residues on metal binding site behavior

Metallacrown Project





Evan Trivedi | Post-Doc | E-mail
Undergraduate Institution: Purdue University
PhD Insitution: Northwestern University
Research Interests: Synthetic chemistry is the basis of my research with applications in homogeneous catalysis, molecular imaging, and medicine

David Chow | Ph.D. Candidate | E-mail
Undergraduate Institution: Western Washington University
Research Interests: He is currently working on the metallacrown project, studying the role of electron spin and magnetic anisotropy in single-molecule magnets.
Jake Lutter | Rotation Studen | E-mail
Undergraduate Institution: Shippensburg University
Research Interests: I am interested in inorganic synthetic chemistry, specifically in metallacrown compounds and their properties.  My research investigates the magnetic behavior (single molecule magnets) and luminescent capabilities of certain metallacrown compounds.
Ying (Kitty) Zhang| Undergraduate | E-mail
Undergraduate Institution: University of Michigan, Ann Arbor
Research Interests: Synthesize of metallacrowns containing lanthanides for future applications such as optical imaging

 

Former Members

Metallopeptide Project (degree received), current position:

  • Dr. Saumen Chakraborty (Ph. D. ), postdoc, Univ. of Illinois at Urbana Champaign.
  • Dr. Kosh Neupane (postdoc), postdoc, Tufts University.
  • Dr. Kimber Clark-Baldwin (postdoc), Research Scientist, Univ. Cincinnati Medical School.
  • Dr. Carol M. Gorst (postdoc), Application Scientist at MSI.
  • Dr. Gregg Dieckmann (Ph.D.), Associate Professor, University of Texas at Dallas.
  • Joel Galang (MS).
  • Susan L. Heilman (MS).
  • Jan Kosinski (MS).
  • Dr. Ryan Fields (BS), M.D.
  • Kirk Jobe (BS Honors), M.D.
  • Kristen Balchus (research rotation).
  • Nzinga Harris (REU).
  • Zikiya Norton (research rotation), Graduate Student, University of Michigan.
  • Melissa Hindenlang (research rotation), Graduate Student, University of Michigan.
  • Soumya Mitra (research rotation), Gradute Student Ohio State University.
  • Dr. Brian Farrer (Postdoc), Senior Research Chemist, Merck.
  • Dr. Wojciech Lesniak (Postdoc) Research Associate, Roswell Park Cancer Institute, Department of Radiation Medicine.
  • Dr. Manolis Matzapetakis (Graduate Student), Post Doc, Children's Hospital Oakland Research Institute.
  • Dr. Kyung Hoon Lee (Postdoc), Assistant Professor, University of South Alabama.
  • Dr. Chris Cabello (Graduate Student), University of Arizona, College of Pharmacy Medicinal Chemistry Program.
  • Dr. Debdip Ghosh (Graduate Student), Post Doc, National Institues of Health (NIH / NIDDK).
  • Dr. Debbie Touw (Graduate Student), Post Doc, Program in Molecular Medicine, University of Massachussetts Medical School.
  • Dr. Marek Luczkowski (Postdoc), Faculty of Chemistry, University of Wroclaw, Poland .
  • Dr. Olga Iranzo (Postdoc), Research Scientist, Bioinorganic Chemistry and Peptide design Division, Instituto de Tecnologia Quimica e Biologica Av. da Republica Estacao Agronomica Nacional (EAN).
  • Dr. Anna Peacock (Postdoc), Lecturer in Chemistry, University of Birmingham,UK.

Vanadium Project (degree received), current position:


Manganese Project (degree received), current position:


Metallacrown Project (degree received), current position:

  • Dr. Joseph Jankolovits (Ph. D.), postdoc, University of California, Berkeley.
  • Dr. Thaddeus Boron (Ph. D.), Assistant Professor, Slippery Rock University
  • Joseph Grant (BS) University of Michigan, (Graduate Student) University of Wisconsin, Madison
  • Dr. Curtis M. Zaleski (Ph. D.), Associate Professor, Shippensburg University of Pennsylvania, PA.

Gentamicin Project (degree received), current position:


Metallopeptide Precursor Projects (degree received), current position:

  • Dr. Linda M. Briggs (Ph.D.): Cloning and Regulation of Synechocystis PCC 6803 Plastocyanin, Research Scientist, Ford Motor Company.
  • Dr. David J. Detlefsen (Ph.D.): Protein-Protein and Protein-Metal Interactions, Senior Research Scientist, Novatia.
  • Mary Taylor (B.S.), M.D.

Research Collaborators