References
Pineapples are one of Hawaii's most valuable crops. Many foreign customers rely on the islands to produce pineapples. Similarly, scientists rely on each other to produce reliable data that they can use in their research. That can be seen with our reaction, which had two cited sources associated with it.
One of the references cited by our reaction was: Gong, J.; Lin, G.; Sun, W.; Li, C.-C.; Yang, Z. J. Am. Chem. Soc. 2010, 132, 16745-16746.
The other was: Peng, F.; Danishefsky, S. J. J. Am. Chem. Soc. 2012, 134, 18860-18867. In this paper, the researchers were also concerned with the total synthesis of maoecrystal V, but they took a different pathway to get to the final molecule. Our paper mentioned how the Peng and Danishefsky article had reported a problem with stereoselectivity when installing the methyl group, which is the group that attaches in our mechanism, because it had 1:1 diastereoselectivity when the epoxidation occurred. Lu and peers claimed to have resolved that issue with their synthesis because methylation was accomplished with 7:1 diastereoselectivity with ketone 60 as the substrate.
Our reaction (60-61):
Peng/Danishefsky article regarding similar methyl:
Other papers have cited the Peng and Danishefsky article and used some of their chemistry.
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