Enantioselective Synthesis of (−)-Maoecrystal V by Enantiodetermining C−H Functionalization

Schematic


Ni hao! Welcome to China, one of the world's oldest and most prosperous empires! We are home to many wonders, including the Great Wall of China, the Forbidden City, the Yellow River, and best of all, Maoecrystal V!

Maoecrystal V is an organic compound found in plants. It has high potential for anti-cancer medication, and the plants from which Maoecrystal V can be derived are found here in China and are used in traditional medicines! We will be exploring one of the steps in a chemical synthesis of this compound! Join us!

Brought to you by your humble tour guides: Brandon Dailey, Heather Calcaterra, and Harrison Hou


Reference:
Lu, P.; Mailyan, A.; Gu, Z.; Guptill, D. M.; Wang, H.; Davies, H. M. L.; Zakarian, A. J. Am. Chem. Soc. 2014, 136, 17738-17749.

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