eRAM Release 2.1.1
12/10/2012
The following changes were included in the 2.1.1. release:
Protocol Question Changes
1. General Information page:
Existing question |
Explain why animals must be used to accomplish your proposed work. |
Text added to existing question |
Further explain why cell or tissue culture, isolated organ preparations, or computer simulations cannot be used. |
2. Sponsor/Funding page:
Text added to Help section (top of page) |
Include all sources of funding that will be used to support the work under this protocol |
3. Location page:
Previous wording of Help section (top of page) |
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New wording of Help section (top of page) |
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4. Species page:
New requirement |
The Quarantine and Conditioning section of questions are now required for ALL species, regardless of USDA classification. |
Previous wording of question |
Justify species selected. |
New wording of question |
Justify the species selected and indicate why a lesser sentient species cannot be used. |
Previous wording of question |
Will environmental enrichment be provided? |
New wording of question |
Will you be providing enrichment? |
New conditional question (if Will you be providing enrichment is NO) |
Justify circumstances where animals will not be provided enrichment. |
New wording of conditional question (if Will you be providing enrichment is YES) |
Describe the enrichment that will be provided (e.g., social housing (rodents only), toys, treats). |
Previous wording of question |
Justify not group housing animals. |
New wording of question |
Provide scientific or veterinary justification for singly housing animals. |
New question |
Will animals be habituated/conditioned to routine husbandry or experimental procedures prior to initiating the study? |
New conditional question (if Will animals be habituated/conditioned to routine husbandry or experimental procedures prior to initiating the study? is NO) |
Explain why habituation/conditioning will not be initiated. |
5. Procedures page, Breeding detail:
New question |
Describe how your colony will be managed to meet your research goals and objectives according to the principles of animal reduction and the methods used to prevent overcrowding. |
6. Procedures page, Hazardous Agents detail:
Previous wording of question |
Does the material pose a hazard to laboratory employees (through direct contact with the hazard or direct or indirect contact with animal or bedding)? |
New wording of question |
Does the material pose a hazard to laboratory employees (through direct contact with the hazard (including those genetically modified animals administered this agent) or direct or indirect contact with animal or bedding)? |
Previous wording of question |
Does the material pose a hazard to facility personnel (through direct contact with the hazard or direct or indirect contact with animal or bedding)? |
New wording of question |
Does the material pose a hazard to facility personnel (through direct contact with the hazard (including those genetically modified animals administered this agent) or direct or indirect contact with animal or bedding)? |
7. Procedures page, Surgery detail:
Previous wording of question |
Will animals undergo more than one major surgical procedure from which they are allowed to recover while under this protocol? |
New wording of question (removed the word 'major') |
Will animals undergo more than one surgical procedure from which they are allowed to recover while under this protocol? |
8. Adverse Consequences page:
Previous wording of question |
Describe expected adverse physical and/or physiological consequences or adverse effects on well-being that the animals may experience as a result of the procedures. |
New wording of question |
Describe expected adverse physical and/or physiological consequences (including genetically modified animals and their specific phenotypes) or adverse effects on well-being that the animals may experience as a result of the procedures. |
New question |
Will the ULAM Veterinary staff be consulted if pain or distress goes beyond the level anticipated in the protocol? |
New conditional question (if Will the ULAM Veterinary staff be consulted if pain or distress goes beyond the level anticipated in the protocol?is NO) |
Provide justification for why the veterinary staff will not be consulted. |
9. Use Justification page:
Existing question |
Justify the number of animals needed to achieve the scientific aim(s) of the project. |
Text added to existing |
Animal numbers should be justified by statistical analysis whenever possible. |
New conditional question if animals will be used in Categories 7, 8 and/or 9 |
Provide specific scientific justification, including references if possible, for why animals must experience pain/distress, cannot receive analgesics, or why death must be used as an endpoint. |
Animal Use Forms
For Animal Transfer form types, there is now a direct relationship between Fee for Service protocols and those protocols that list Fee for Service protocols on their procedure details. For example, if a Fee for Service protocol starts a transfer form, the only protocols that they will be able to select are those that list that particular Fee for Service on their procedure detail. |
On the Animal Purchase Request and ULAM Delivery Notification animal use types, a new option was added to specify "Other" as an Animal Measure type instead of specifying age or weight. If this option is used, then a note describing the request (e.g., 2 months pregnant) must be entered in the Special Instructions/Notes to ULAM prior to submission. |
UCUCA/ULAM
For Animal Transfer form types, Fee for Service protocols upon approval will no longer automatically move into a Completed state when breeding sheets and/or cage cards are needed. This signals ULAM that processing is needed in these circumstances. |