cbi
 

CHEMISTRY BIOLOGY INTERFACE
TRAINING PROGRAM

Student Sabbaticals

As part of the CBI Training Program it is a requirement that all appointed students complete a Student Sabbatical by the end of your graduate studies (preferably by the end of 4.5 years in the graduate program). The Student Sabbatical proposal must be submitted by July 1 of the end of the student's first year of support.  The proposal must be approved by the CBI Program Committee before funding for the appointed student is terminated.  Once the student has returned to the University of Michigan, from the Sabbatical, a one-two page written report, describing the entire experience, will be due within 30 days. The background of the Student Sabbatical is as follows:

  • Students will write a proposal that outlines an “advanced rotation experience”, preferably in a research collaborators laboratory. The site of the 10 week sabbatical may be in academe, industry, or government laboratories. These laboratories may be physically located in Ann Arbor, but will preferably be located outside the Uniuversity of Michigan, possibly in more distant sites, including out of state and overseas.
  • It is expected that the student will physically move to the laboratory of the collaborator for the period of the sabbatical. If necessary, the sabbatical may be done over more than one visit.
  • The proposal should describe a self-contained project that is relevant to the student’s thesis work.
  • A letter of approval by the advisor shall be obtained and submitted within the package.
  • A letter of agreement from the host scientist shall be obtained and submitted within the package.
  • At the end of the sabbatical, a short report of research experience will be submitted to the program committee.  This report is due within one month of completion of the Sabbatical.
  • Advisors, for each Fellow, will receive correspondence on all communications regarding the sabbatical.

The format and requirements of the Student Sabbatical Proposal are as follows:

  • Cover Page (see attached .pdf file)
  • Letter of Support from Sabbatical Host
  • Letter of Support from the students Advisor
  • Proposal Letter (minimum of three pages and a maximum of five)

The requirements of the 3-5 page Proposal Letter are as follows:

  • Background of Research/Studies at U of M
  • Preliminary Work – explanation of ongoing work in your lab
  • Actual proposal of the work to be completed at the Host location lab/industry
  • Explanation of how the work completed on your Sabbatical relates to your thesis research at U of M.

Student Sabbatical Proposals

Year Student Mentor Host Location
Project Title
2012 Conor Doss Anna Mapp Quintin Pan Ohio State University Phenotypic and specific cell fate consequences of Inhibiting the p300/CH1 on NANOG expression in cancer cells
2012 Frank Kwarcinski Matthew Soellner Markus Seeliger; Jeanne A. Stuckey Stony Brook University NY; UM Ann Arbor Selective irreversible c-­-Src inhibitors to explore kinase P-­-loop conformations through protein crystallization and crystal structure of the c-Yes enzyme
2012 Erin Miller Patrick O'Brien Leona Samson MIT The study of AlkB, another bacterial DNA repair protein
2012 Carol Ann Pitcairn Carol Fierke Geeta Narlikar UCalifornia-SF Reconstituting chromatin from recombinant components and ising a variety of biophysical approaches to study how chromatin structure is altered by chromatin remodeling enzymes
2012 Alison Tebo Vincent Pecoraro Ally Aukauloo Université Paris-Sud 11 Techniques to selectively label peptides with Ru(bpy) chromophores for the measurement of electron transfer rates between the designed iron center in the peptide and the chromophore
           
2011 Steffen Bernard Janet Smith David Sherman UM, Ann Arbor

Synthesis of Substrate Mimics to Probe Substrate Specificity in Polyketide Synthase
Ketoreductase Domains
2011 Derek Lyons Patrick O'Brien Thomas E. Wilson UM, Ann Arbor

Alteration of Frameshift Mutation Rate Resulting from Imbalanced DNA Repair
2011 Ronald Jenkins Garry Dotson Jeanne Stuckey UM, Ann Arbor

Probing Early Acyltransferases of Lipid A Biosynthesis: A Crystallographic Study
2011 Christopher Taylor Anna Mapp Colin Duckett UM, Ann Arbor

Identification of molecules that modulate the activity of the activator NF-kappaB
2011 Solymar Negretti John Montgomery David Sherman UM, Ann Arbor

Isolation of Natural Product Intermediates Narbonolide and 10-deoxymethynolide & Biological Evaluation of PikC Unnatural Substrates:
PikC Oxidation Studies and Antibacterial Assays
2011 Jonathan Whicher Janet Smith David Sherman UM, Ann Arbor

Characterization of docking domains from the curacin A biosynthetic pathway
Completion Report
2011 Melissa Zastrow VPecoraro Fraser A. Armstrong Oxford University, London UK Electrochemical studies on copper bound in a His3 coordination environment in peptides of the TRI family
Sabbatcial Completion Report
           
2009 Dustin Patterson Neil Marsh Mark Banaszak Holl UM, Ann Arbor Imaging proteins by Atomic Force Microscopy (AFM)
2009 James Patrone Garry Dotson Jeanne Stuckey UM, Ann Arbor Intermediate-Based Inhibitors of Phosphopantothenoylcysteine Synthetase: A Crystallographic Study

2009 Matthew Leathen John Wolfe Amgen Inc. Cambridge, Massachusetts

Facile preparation of protected benzylic and heteroarylmethyl amines via room temperature Curtius rearrangement
Sabbatical Completion Report
           
2005 Curtis Schneider VPecoraro Luca DiGioia Milan, Italy

Mechanism of Oxo Transfer Ligands: A DFT Investigation (.doc)
EJIC article (pdf)

           
2006 Sara Buhrlage AMapp David Wemmer Berkeley, CA Small Molecules for Targeting Protein Surfaces
           
2007 Edgar Lee AGafni Bradd Orr UM Mechanisms of Islet Amyloid Polypeptide Oligomerization Investigated with Atomic Force Microscopy
           
           

 

For more information about the CBI Training Grant E-mail: CBI.Gen.Info@umich.edu